Results 61 to 70 of about 17,069 (317)
Neuroimmune Regulation of Surgery-Associated Metastases
Cells, 2021 Surgery remains an essential therapeutic approach for most solid malignancies. Although for more than a century accumulating clinical and experimental data have indicated that surgical procedures themselves may promote the appearance and progression of ...
Michael R. Shurin +2 more
doaj +1 more source
Tumor-neuroglia interaction promotes pancreatic cancer metastasis
Theranostics, 2020 Rationale: The peripheral nervous system (PNS) plays an important role in tumor growth and progression. Schwann cells (SCs), the main glia cells of the PNS, augment cancer metastasis in contact-dependent or contact-independent manner in various ...
D. Su +7 more
semanticscholar +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger +2 more
wiley +1 more source
Effects of Cabergoline and Levetiracetam on the Histological and Stereological Structure of the Cerebral Cortex, Hippocampus and Cerebellum of Rats With Pentylenetetrazol-Induced Seizure [PDF]
مجله دانشگاه علوم پزشکی گیلان, 2023 Background: Epilepcy is a chronic neurological disease, and due to its complex mechanism, the current therapeutic drugs for it are not effective enough. It may have a non-neurological origin such as astrocytes and microglia.
Mohammad Hossein Hajati Pishvari +2 more
doaj
Differentiation of Mesenchymal Stem Cells to Neuroglia: in the Context of Cell Signalling
Stem Cell Reviews and Reports, 2019 The promise of engineering specific cell types from stem cells and rebuilding damaged or diseased tissues has fascinated stem cell researchers and clinicians over last few decades.
S. George +2 more
semanticscholar +1 more source
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
NeurogliaExtracellular vesicles (EVs), including exosomes and microvesicles, are membrane-bound particles released by cells into extracellular space. These vesicles carry various molecules, such as proteins and lipids, and can serve as mediators of intercellular ...
Parisa Gazerani
doaj +1 more source
Breast milk stem cells: four questions looking for an answer
Journal of Pediatric and Neonatal Individualized Medicine, 2016 The finding of stem/progenitor cells in the maternal milk and the discovery of their multilineage potential, associated with some evidence regarding the ability of maternal cells to cross the gastrointestinal barrier and integrate into the organs of the ...
Gavino Faa +7 more
doaj +1 more source
NeurogliaBackground: The primary co-occurrence of gonadal and extragonadal central nervous system (CNS) germ cell tumors (GCTs) has rarely been reported in the literature, and a common opinion on the underlying etiopathogenetic mechanism is lacking. Objective: We
Francesco Tengattini +8 more
doaj +1 more source