Results 41 to 50 of about 15,147 (194)

Astrocytes as a target for therapeutic strategies in epilepsy: current insights

Frontiers in Molecular Neuroscience, 2023
Astrocytes are specialized non-neuronal glial cells of the central nervous system, contributing to neuronal excitability and synaptic transmission (gliotransmission). Astrocytes play a key roles in epileptogenesis and seizure generation.
Nihan Çarçak, Nihan Çarçak, Filiz Onat, Filiz Onat, Evgenia Sitnikova   +4 more
doaj   +1 more source

Neuroglia infection by rabies virus after anterograde virus spread in peripheral neurons [PDF]

, 2020
The highly neurotropic rabies virus (RABV) enters peripheral neurons at axon termini and requires long distance axonal transport and trans-synaptic spread between neurons for the infection of the central nervous system (CNS).
Zaeck, Luca M., Müller, Thomas, Freuling, Conrad M., Potratz, Madlin, Weigel, Carlotta, Freuling, Conrad Martin, Klein, Antonia, Finke, Stefan, Zaeck, Luca Mirko   +8 more
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Clearance Systems in the Brain, From Structure to Function

Frontiers in Cellular Neuroscience, 2022
As the most metabolically active organ in the body, there is a recognized need for pathways that remove waste proteins and neurotoxins from the brain. Previous research has indicated potential associations between the clearance system in the brain and ...
Jiachen Liu, Yunzhi Guo, Chengyue Zhang, Yang Zeng, Yongqi Luo, Gaiqing Wang, Gaiqing Wang   +6 more
doaj   +1 more source

Neuronal Glial Crosstalk: Specific and Shared Mechanisms in Alzheimer’s Disease

Brain Sciences, 2022
The human brain maintains billions of neurons functional across the lifespan of the individual. The glial, supportive cells of the brain are indispensable to neuron elasticity.
Vishal Chavda, Kavita Singh, Vimal Patel, Meerambika Mishra, Awdhesh Kumar Mishra   +4 more
doaj   +1 more source

The Role of Neuroglia in Neurodevelopmental Disorders and Disruptive Behavior: A Broad Review of Current Literature

Neuroglia
Neurodevelopmental disorders represent a significant health concern, leading to a wide range of clinical, cognitive, and social impairments. Although the exact causes of these disorders remain unclear, genetic, epigenetic, and environmental factors all ...
Samet Çetin, Serap Uysal, Dilara Girgin, Ayşenur Alp, Ecem Kiliç, Oğulcan Çiray   +5 more
doaj   +1 more source

Release of VAMP5‐positive extracellular vesicles by retinal Müller glia in vivo

Journal of Extracellular Vesicles, 2022
Cell‐cell interactions in the central nervous system are based on the release of molecules mediating signal exchange and providing structural and trophic support through vesicular exocytosis and the formation of extracellular vesicles.
Valerie Demais, Anne Pohl, Kirsten A. Wunderlich, Anna M. Pfaller, Lew Kaplan, Amelie Barthélémy, Robin Dittrich, Berta Puig, Bernd Giebel, Stefanie M. Hauck, Frank W. Pfrieger, Antje Grosche   +11 more
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Elucidating the neuroimmunology of traumatic brain injury: methodological approaches to unravel intercellular communication and function

Frontiers in Cellular Neuroscience, 2023
The neuroimmunology of traumatic brain injury (TBI) has recently gained recognition as a crucial element in the secondary pathophysiological consequences that occur following neurotrauma. Both immune cells residing within the central nervous system (CNS)
Hadi Abou-El-Hassan, Joshua D. Bernstock, Joshua D. Bernstock, Joshua I. Chalif, Taha Yahya, Rafael M. Rezende, Howard L. Weiner, Saef Izzy   +7 more
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Studying neurodegenerative diseases in culture models

Brazilian Journal of Psychiatry, 2013
Neurodegenerative diseases are pathological conditions that have an insidious onset and chronic progression. Different models have been established to study these diseases in order to understand their underlying mechanisms and to investigate new ...
Johannes C.M. Schlachetzki, Soraya Wilke Saliba, Antonio Carlos Pinheiro de Oliveira   +2 more
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AllenInstitute/neuroglia v0.2.10

, 2018
a Python machine learning library for neurophysiology ...
NileGraddis, Justin Kiggins, Sahar, nicain, Johannes Friedrich, mochic, Michael Oliver   +6 more
core   +1 more source

Beyond the Neuron: The Integrated Role of Glia in Psychiatric Disorders

Neuroglia
In recent decades, substantial evidence has highlighted the integral roles of neuroglia, particularly astrocytes, microglia, oligodendrocytes, and ependymal cells, in the regulation of synaptic transmission, metabolic support, and immune mechanisms ...
André Demambre Bacchi
doaj   +1 more source