Results 21 to 30 of about 15,346 (302)

The role of glial cells in neurodegenerative diseases. Part 2. Glial cells pathophysiology in neurodegeneration [PDF]

open access: yesFarmacja Polska, 2022
The proper operation of the nervous system is strongly dependent on the interactions between neurons and glial cells. Thus, the disturbance of their relationship leads to various neurological complications.
Mateusz Maszczyk   +2 more
doaj   +1 more source

General pathophysiology of neuroglia

open access: greenHandbook of Clinical Neurology / Edited By P J Vinken and G W Bruyn
Elly Hol   +2 more
exaly   +3 more sources

Damaged Neocortical Perineuronal Nets Due to Experimental Focal Cerebral Ischemia in Mice, Rats and Sheep

open access: yesFrontiers in Integrative Neuroscience, 2017
As part of the extracellular matrix (ECM), perineuronal nets (PNs) are polyanionic, chondroitin sulfate proteoglycan (CSPG)-rich coatings of certain neurons, known to be affected in various neural diseases.
Wolfgang Härtig   +11 more
doaj   +1 more source

Epoxyeicosatrienoic acids and soluble epoxide hydrolase in physiology and diseases of the central nervous system

open access: yesChinese Journal of Physiology, 2022
Epoxyeicosatrienoic acids (EETs) are fatty acid signaling molecules synthesized by cytochrome P450 epoxygenases from arachidonic acid. The biological activity of EETs is terminated when being metabolized by soluble epoxide hydrolase (sEH), a process that
Yi-Min Kuo, Yi-Hsuan Lee
doaj   +1 more source

Neuroimmune Regulation of Surgery-Associated Metastases

open access: yesCells, 2021
Surgery remains an essential therapeutic approach for most solid malignancies. Although for more than a century accumulating clinical and experimental data have indicated that surgical procedures themselves may promote the appearance and progression of ...
Michael R. Shurin   +2 more
doaj   +1 more source

Soursop leaf extract increases neuroglia and hepatic degeneration in female rats

open access: yesUniversa Medicina, 2016
BACKGROUND Soursop leaf contains annonaceous acetogenins and alkaloids. The acetogenins act as inhibitors of mitochondrial complex I, suppress ATP production and cause cell degeneration, whereas the alkaloids act as neurotoxins.
Ety Sri Handayani   +2 more
doaj   +1 more source

Pathophysiology of Lipid Droplets in Neuroglia

open access: yesAntioxidants, 2021
In recent years, increasing evidence regarding the functional importance of lipid droplets (LDs), cytoplasmic storage organelles in the central nervous system (CNS), has emerged.
Tina Smolič, Robert Zorec, Nina Vardjan
doaj   +1 more source

A Milled Microdevice to Advance Glia-Mediated Therapies in the Adult Nervous System

open access: yesMicromachines, 2019
Neurodegenerative disorders affect millions of adults worldwide. Neuroglia have become recent therapeutic targets due to their reparative abilities in the recycling of exogenous neurotoxins and production of endogenous growth factors for proper ...
Juan S. Peña   +3 more
doaj   +1 more source

Head-to-Head Study of Developmental Neurotoxicity and Resultant Phenotype in Rats: α-Hexabromocyclododecane versus Valproic Acid, a Recognized Model of Reference for Autism Spectrum Disorders

open access: yesToxics, 2022
Evidence is now growing that exposure to environmental pollutants during the critical early-life period of brain development may contribute to the emergence of Autism Spectrum Disorders (ASD).
Chloé Morel   +6 more
doaj   +1 more source

The role of glial cells in neurodegenerative diseases. Part 1. Characteristics and physiological functions [PDF]

open access: yesFarmacja Polska, 2022
The nervous system is composed of two dominant types of cells – neurons and glial cells. They differ from each other both morphologically and physiologically.
Mateusz Maszczyk   +2 more
doaj   +1 more source

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