Results 21 to 30 of about 15,147 (194)

Multi-Target Effects of ß-Caryophyllene and Carnosic Acid at the Crossroads of Mitochondrial Dysfunction and Neurodegeneration: From Oxidative Stress to Microglia-Mediated Neuroinflammation

open access: yesAntioxidants, 2022
Inflammation and oxidative stress are interlinked and interdependent processes involved in many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases, and cancer.
Roberto Iorio   +2 more
doaj   +1 more source

Parapharyngeal Neuroglial Heterotopia: A Case Report [PDF]

open access: yesIranian Journal of Neonatology, 2022
Background: Neonatal neck masses usually fall into three categories: developmental, inflammatory, and neoplastic. Malignant neck masses are rarely observed in neonates; nonetheless, If malignancy is suspected, the patient should be evaluated urgently. In
Reza Saeidi   +4 more
doaj   +1 more source

The role of glial cells in neurodegenerative diseases. Part 2. Glial cells pathophysiology in neurodegeneration [PDF]

open access: yesFarmacja Polska, 2022
The proper operation of the nervous system is strongly dependent on the interactions between neurons and glial cells. Thus, the disturbance of their relationship leads to various neurological complications.
Mateusz Maszczyk   +2 more
doaj   +1 more source

Neuroglia—An Open Access Journal

open access: yes, 2021
Welcome to Neuroglia, a new Open Access MDPI journal which will report original research articles and reviews on studies of neuroglia [...
James St John
core   +1 more source

Damaged Neocortical Perineuronal Nets Due to Experimental Focal Cerebral Ischemia in Mice, Rats and Sheep

open access: yesFrontiers in Integrative Neuroscience, 2017
As part of the extracellular matrix (ECM), perineuronal nets (PNs) are polyanionic, chondroitin sulfate proteoglycan (CSPG)-rich coatings of certain neurons, known to be affected in various neural diseases.
Wolfgang Härtig   +11 more
doaj   +1 more source

Epoxyeicosatrienoic acids and soluble epoxide hydrolase in physiology and diseases of the central nervous system

open access: yesChinese Journal of Physiology, 2022
Epoxyeicosatrienoic acids (EETs) are fatty acid signaling molecules synthesized by cytochrome P450 epoxygenases from arachidonic acid. The biological activity of EETs is terminated when being metabolized by soluble epoxide hydrolase (sEH), a process that
Yi-Min Kuo, Yi-Hsuan Lee
doaj   +1 more source

Neuroimmune Regulation of Surgery-Associated Metastases

open access: yesCells, 2021
Surgery remains an essential therapeutic approach for most solid malignancies. Although for more than a century accumulating clinical and experimental data have indicated that surgical procedures themselves may promote the appearance and progression of ...
Michael R. Shurin   +2 more
doaj   +1 more source

Head-to-Head Study of Developmental Neurotoxicity and Resultant Phenotype in Rats: α-Hexabromocyclododecane versus Valproic Acid, a Recognized Model of Reference for Autism Spectrum Disorders

open access: yesToxics, 2022
Evidence is now growing that exposure to environmental pollutants during the critical early-life period of brain development may contribute to the emergence of Autism Spectrum Disorders (ASD).
Chloé Morel   +6 more
doaj   +1 more source

A Milled Microdevice to Advance Glia-Mediated Therapies in the Adult Nervous System

open access: yesMicromachines, 2019
Neurodegenerative disorders affect millions of adults worldwide. Neuroglia have become recent therapeutic targets due to their reparative abilities in the recycling of exogenous neurotoxins and production of endogenous growth factors for proper ...
Juan S. Peña   +3 more
doaj   +1 more source

Metabotropic Glutamate Receptor 5 Antagonism Reduces Pathology and Differentially Improves Symptoms in Male and Female Heterozygous zQ175 Huntington’s Mice

open access: yesFrontiers in Molecular Neuroscience, 2022
Huntington’s disease (HD) is an inherited autosomal dominant neurodegenerative disorder that leads to progressive motor and cognitive impairment. There are currently no available disease modifying treatments for HD patients. We have previously shown that
Si Han Li   +8 more
doaj   +1 more source

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