Results 11 to 20 of about 16,138 (287)
The Impact of Neuroglia on Vestibular Disorders: Insights and Implications
Neuroglia (Basel, Switzerland)Vestibular disorders significantly affect individuals by impairing balance, spatial orientation, and quality of life. Despite the focus on neuronal mechanisms, emerging research emphasizes the importance of neuroglia—astrocytes, microglia ...
Melissa Castillo‐Bustamante +2 more
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The Concept of Neuroglia [PDF]
, 2019 Neuroglia represent a diverse population of non-neuronal cells in the nervous systems, be that peripheral, central, enteric or autonomic nervous system. Arguably, these cells represent about half of the volume of the human brain. This volumetric ratio, and by extension glia to neurone ratio, not only widely differ depending on the size of the animal ...
Verkhratsky, Alexei +3 more
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, 2019 Ageing reduces the functional capacity of all organs, so does that of the nervous system; the latter is evident in the reduction of cognitive abilities, learning and memory. While the exact mechanisms of ageing of the nervous system remain elusive, it is without doubt that morpho-functional changes in a variety of neuroglial cells contribute to this ...
Verkhratsky, Alexei +3 more
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Pathophysiology of Lipid Droplets in Neuroglia
Antioxidants, 2021 In recent years, increasing evidence regarding the functional importance of lipid droplets (LDs), cytoplasmic storage organelles in the central nervous system (CNS), has emerged.
Tina Smolič, Robert Zorec, Nina Vardjan
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, 2019 As the nervous system evolved from the diffused to centralised form, the neurones were joined by the appearance of the supportive cells, the neuroglia. Arguably, these non-neuronal cells evolve into a more diversified cell family than the neurones are. The first ancestral neuroglia appeared in flatworms being mesenchymal in origin.
Verkhratsky, Alexei +2 more
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Unraveling the Critical Mechanisms and Functions of Neuroglia in Spinal Cord Injuries
Neuroglia, 2023 In the dynamic landscape of neuroscience and regenerative medicine, the pivotal role of neuroglia, or glial cells, is increasingly being recognized [...]
Chih-Wei Zeng
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Epistemological implications of astroglia scientific research [PDF]
Frontiers in Cellular NeuroscienceNeuroglia, comprising three cell types (astrocytes, oligodendrocytes and microglia), interact with neurons and extracellular components in brain physiology.
Alfredo Pereira +2 more
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P2X receptors in neuroglia [PDF]
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2012 AbstractDifferent types of ionotropic P2X purinoceptors are expressed in all major types of neuroglia, where they mediate a variety of physiological and pathological signaling. Cortical astrocytes express specific P2X1/5 heteromeric receptors that are activated by ongoing synaptic transmission and can trigger fast local signaling through elevation in ...
Verkhratsky, A.; id_orcid 0000-0003-2592-9898 +3 more
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Neuroglia in the healthy brain
The nervous tissue is composed of neurons and neuroglia, which by working in a tightly coordinated manner, define the function of the nervous system. Neuroglia, defined as homeostatic and defensive cells of the nervous system, are highly heterogeneous in form and function and are endowed with a remarkable plasticity that allows life-long adaptation to ...
Verkhratsky, A. +4 more
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The Role of Neuroglia in the Development and Progression of Schizophrenia [PDF]
BiomoleculesSchizophrenia is a complex heterogenous disorder thought to be caused by interactions between genetic and environmental factors. The theories developed to explain the etiology of schizophrenia have focused largely on the dysfunction of neurotransmitters ...
Neha S. Rawani +4 more
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