Results 11 to 20 of about 21,830 (258)

Epoxyeicosatrienoic acids and soluble epoxide hydrolase in physiology and diseases of the central nervous system

open access: yesChinese Journal of Physiology, 2022
Epoxyeicosatrienoic acids (EETs) are fatty acid signaling molecules synthesized by cytochrome P450 epoxygenases from arachidonic acid. The biological activity of EETs is terminated when being metabolized by soluble epoxide hydrolase (sEH), a process that
Yi-Min Kuo, Yi-Hsuan Lee
doaj   +1 more source

Neuroimmune Regulation of Surgery-Associated Metastases

open access: yesCells, 2021
Surgery remains an essential therapeutic approach for most solid malignancies. Although for more than a century accumulating clinical and experimental data have indicated that surgical procedures themselves may promote the appearance and progression of ...
Michael R. Shurin   +2 more
doaj   +1 more source

Mozart KV 448 Menurunkan Densitas dan Aktivitas Neuroglia Hipokampus Mencit (Mus Musculus) Selama Stres Prenatal No. 416-KE [PDF]

open access: yes, 2017
The aim of this research was to explore the influence of Mozart KV 448 classical music therapy to the neuroglia cells of mice's hippocampus that were exposed to stress during prenatal.
Hestianah, E. P. (Eka)   +4 more
core   +5 more sources

Soursop leaf extract increases neuroglia and hepatic degeneration in female rats

open access: yesUniversa Medicina, 2016
BACKGROUND Soursop leaf contains annonaceous acetogenins and alkaloids. The acetogenins act as inhibitors of mitochondrial complex I, suppress ATP production and cause cell degeneration, whereas the alkaloids act as neurotoxins.
Ety Sri Handayani   +2 more
doaj   +1 more source

Pathophysiology of Lipid Droplets in Neuroglia

open access: yesAntioxidants, 2021
In recent years, increasing evidence regarding the functional importance of lipid droplets (LDs), cytoplasmic storage organelles in the central nervous system (CNS), has emerged.
Tina Smolič, Robert Zorec, Nina Vardjan
doaj   +1 more source

Head-to-Head Study of Developmental Neurotoxicity and Resultant Phenotype in Rats: α-Hexabromocyclododecane versus Valproic Acid, a Recognized Model of Reference for Autism Spectrum Disorders

open access: yesToxics, 2022
Evidence is now growing that exposure to environmental pollutants during the critical early-life period of brain development may contribute to the emergence of Autism Spectrum Disorders (ASD).
Chloé Morel   +6 more
doaj   +1 more source

Brain macrophages in human cortical contusions as indicator of survival period [PDF]

open access: yes, 1986
The aim of this study was to establish a morphologic time scheme with which cases of cerebral contusion with unknown survival periods can be dated. Our study of 275 cases was limited to qualitative and quantitative changes in macrophages.
Adams   +36 more
core   +1 more source

A Milled Microdevice to Advance Glia-Mediated Therapies in the Adult Nervous System

open access: yesMicromachines, 2019
Neurodegenerative disorders affect millions of adults worldwide. Neuroglia have become recent therapeutic targets due to their reparative abilities in the recycling of exogenous neurotoxins and production of endogenous growth factors for proper ...
Juan S. Peña   +3 more
doaj   +1 more source

Metabotropic Glutamate Receptor 5 Antagonism Reduces Pathology and Differentially Improves Symptoms in Male and Female Heterozygous zQ175 Huntington’s Mice

open access: yesFrontiers in Molecular Neuroscience, 2022
Huntington’s disease (HD) is an inherited autosomal dominant neurodegenerative disorder that leads to progressive motor and cognitive impairment. There are currently no available disease modifying treatments for HD patients. We have previously shown that
Si Han Li   +8 more
doaj   +1 more source

Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling. [PDF]

open access: yes, 2018
BACKGROUND:Human cerebral malaria (HCM) is a severe form of malaria characterized by sequestration of infected erythrocytes (IRBCs) in brain microvessels, increased levels of circulating free heme and pro-inflammatory cytokines and chemokines, brain ...
Cespedes, Juan Carlos   +5 more
core   +1 more source

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