Results 31 to 40 of about 21,830 (258)

A new theory of depression based on the serotonin/kynurenine relationship and the hypothalamicpituitary- adrenal axis

Biomédica: revista del Instituto Nacional de Salud, 2018
The serotonergic and immunological hypothesis of depression proposes that certain types of excessive stress distort the relationship between the activities of the innate immune and central nervous systems, so that the stress caused by an infection, or ...
Leslie Alejandra Ramírez, Elsy Arlene Pérez-Padilla, Francisco García-Oscos, Humberto Salgado, Marco Atzori, Juan Carlos Pineda   +5 more
doaj   +1 more source

Neurotoxicity [PDF]

, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust, Creeley, Feldman, Grandjean, Herken, Panzica, Parent, Pessah, Rice, Román, Spencer, Spencer, Tu, Vinken, Yasui, Zawia   +15 more
core   +2 more sources

Widely Spread Butyrylcholinesterase Can Hydrolyze Acetylcholine in the Normal and Alzheimer Brain

Neurobiology of Disease, 2002
Background: Butyrylcholinesterase (BChE), also known as the “pseudo” or “non-neuronal” cholinesterase, is traditionally thought to have a restricted CNS distribution and to play little, if any, role in cholinergic transmission.
Marsel Mesulam, Angela Guillozet, Pamela Shaw, Bruce Quinn   +3 more
doaj   +1 more source

Links between traumatic brain injury and ballistic pressure waves originating in the thoracic cavity and extremities

, 2008
Identifying patients at risk of traumatic brain injury (TBI) is important because research suggests prophylactic treatments to reduce risk of long-term sequelae.
Alexander MP, Amy Courtney, Bruton C, Center for Disease Control and Prevention (CDC), Cernak I, Cernak I, Courtney M, Courtney M, Herrmann M, Krave U, Kushner DS, Kushner DS, Lowenstein DH, Margerison JH, Mayorga MA, Michael Courtney, Newgard K, Scott SG, Shaw NA, Stalnacke BM, Suneson A, Suneson A, Suneson A, Thompson HJ, Toth Z, Treib J, Trudeau DL, Vanderploeg RD, Vink R, Wang Q   +29 more
core   +1 more source

The Impact of Neuroglia on Vestibular Disorders: Insights and Implications

Neuroglia
Vestibular disorders significantly affect individuals by impairing balance, spatial orientation, and quality of life. Despite the focus on neuronal mechanisms, emerging research emphasizes the importance of neuroglia—astrocytes, microglia ...
Melissa Castillo-Bustamante, Andrés Felipe Herrón-Arango, María José Bedoya, Juan José Figueroa, Valeria Rees, Alejandro García   +5 more
doaj   +1 more source

Astrocytes as a target for therapeutic strategies in epilepsy: current insights

Frontiers in Molecular Neuroscience, 2023
Astrocytes are specialized non-neuronal glial cells of the central nervous system, contributing to neuronal excitability and synaptic transmission (gliotransmission). Astrocytes play a key roles in epileptogenesis and seizure generation.
Nihan Çarçak, Nihan Çarçak, Filiz Onat, Filiz Onat, Evgenia Sitnikova   +4 more
doaj   +1 more source

History of Neuroscience: Mesoglia and Microglia [PDF]

, 2007
Microglia are mononuclear phagocytes that reside within the central nervous system (CNS). They differ from macroglia (astrocytes and oligodendrocytes) in terms of their origin, phenotype and functions, but more closely resemble tissue-resident ...
Rezaie, Payam
core  

Differences in magnetic particle uptake by CNS neuroglial subclasses: implications for neural tissue engineering [PDF]

, 2013
AIM: To analyze magnetic particle uptake and intracellular processing by the four main non-neuronal subclasses of the CNS: oligodendrocyte precursor cells; oligodendrocytes; astrocytes; and microglia.
Chari, DM, Furness, DN, Jenkins, SI, Pickard, MR, Yiu, HH   +4 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Clearance Systems in the Brain, From Structure to Function

Frontiers in Cellular Neuroscience, 2022
As the most metabolically active organ in the body, there is a recognized need for pathways that remove waste proteins and neurotoxins from the brain. Previous research has indicated potential associations between the clearance system in the brain and ...
Jiachen Liu, Yunzhi Guo, Chengyue Zhang, Yang Zeng, Yongqi Luo, Gaiqing Wang, Gaiqing Wang   +6 more
doaj   +1 more source