Results 31 to 40 of about 289,843 (294)

Cerebellar remodelling decades after spinal cord insult: neuroplasticity in poliomyelitis survivors

Journal of Integrative Neuroscience, 2022
Background: The cerebellum integrates a multitude of motor and cognitive processes through ample spinal and supratentorial projections. Despite emerging evidence of adaptive neuroplasticity, cerebellar reorganisation in response to severe spinal insult ...
Stacey Li Hi Shing, Aizuri Murad, Jasmin Lope, Orla Hardiman, Peter Bede   +4 more
doaj   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

APOE4 rat model of Alzheimer’s disease: sex differences, genetic risk and diet

BMC Neuroscience
The strongest genetic risk factor for Alzheimer’s disease (AD) is the ε4 allele of apolipoprotein E (ApoE ε4). A high fat diet also adds to the risk of dementia and AD.
Bradley Colarusso, Richard Ortiz, Julian Yeboah, Arnold Chang, Megha Gupta, Praveen Kulkarni, Craig F. Ferris   +6 more
doaj   +1 more source

Neuroimaging in Narcolepsy [PDF]

Sleep Medicine, 2010
Narcolepsy is a chronic neurological disorder, has no specific cause, and is characterized by excessive daytime sleepiness and uncontrollable sleep attacks. In case of strong emotions such as laughter, anger or joy, a cataplexy (sudden loss of muscle tone, lasting for a short period of time) may occur (1, 2).
Hakyemez, BAHATTİN, Bican, AYLİN, Alper, E., Ozkol, V., Algin, O., Bora, I.   +5 more
openaire   +6 more sources

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Kinematic parameters obtained with the ArmeoSpring for upper-limb assessment after stroke: a reliability and learning effect study for guiding parameter use

Journal of NeuroEngineering and Rehabilitation, 2020
Background After stroke, kinematic measures obtained with non-robotic and robotic devices are highly recommended to precisely quantify the sensorimotor impairments of the upper-extremity and select the most relevant therapeutic strategies.
Nabila Brihmat, Isabelle Loubinoux, Evelyne Castel-Lacanal, Philippe Marque, David Gasq   +4 more
doaj   +1 more source

A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis

npj Digital Medicine, 2023
Modern management of MS targets No Evidence of Disease Activity (NEDA): no clinical relapses, no magnetic resonance imaging (MRI) disease activity and no disability worsening.
Michael Barnett, Dongang Wang, Heidi Beadnall, Antje Bischof, David Brunacci, Helmut Butzkueven, J. William L. Brown, Mariano Cabezas, Tilak Das, Tej Dugal, Daniel Guilfoyle, Alexander Klistorner, Stephen Krieger, Kain Kyle, Linda Ly, Lynette Masters, Andy Shieh, Zihao Tang, Anneke van der Walt, Kayla Ward, Heinz Wiendl, Geng Zhan, Robert Zivadinov, Yael Barnett, Chenyu Wang   +24 more
doaj   +1 more source

Alterations in somatosensory, visual and auditory pathways in amyotrophic lateral sclerosis: an under-recognised facet of ALS

Journal of Integrative Neuroscience, 2022
Background: While amyotrophic lateral sclerosis (ALS) is widely recognised as a multi-network disorder with extensive frontotemporaland cerebellar involvement, sensory dysfunction is relatively under evaluated.
Rangariroyashe H. Chipika, Grainne Mulkerrin, Aizuri Murad, Jasmin Lope, Orla Hardiman, Peter Bede   +5 more
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Neuroimaging in Dementia [PDF]

Seminars in Neurology, 2008
Although dementia is a clinical diagnosis, neuroimaging often is crucial for proper assessment. Magnetic resonance imaging (MRI) and computed tomography (CT) may identify nondegenerative and potentially treatable causes of dementia. Recent neuroimaging advances, such as the Pittsburgh Compound-B (PIB) ligand for positron emission tomography imaging in ...
Vitali P., Migliaccio R., Agosta F., Rosen H. J., Geschwind M. D.   +4 more
openaire   +4 more sources