Results 41 to 50 of about 350,469 (317)

Adopting transfer learning for neuroimaging : a comparative analysis with a custom 3D convolution neural network model [PDF]

, 2022
: Background In recent years, neuroimaging with deep learning (DL) algorithms have made remarkable advances in the diagnosis of neurodegenerative disorders.
Martínez-Sanchis, Begoña, Aarsland, Dag,, Bauckneht, Matteo, Ochoa-Figueroa, Miguel, Kramberger, Milica G, Frisoni, Giovanni, Nicastro, Nicolas,, Ochoa-Figueroa, Miguel,, Etminani, Kobra, Camacho, Valle, Chincarini, Andrea, Agudelo-Cifuentes, Marc, Lemstra, Afina W, Stegeran, Roxana,, Berckel, Bart N.M.van,, Chang, Jose R., Nobili, Flavio, Frisoni, Giovanni B.,, Chincarini, Andrea,, Vandenberghe, Rik,, Kramberger, Milica G., Lemstra, Afina W., Morbelli, Silvia,, Padovani, Alessandro,, Aarsland, Dag, Ressner, Marcus,, Frisoni, Giovanni B., Bruffaerts, Rose,, Chang, Jose R.,, Nicastro, Nicolas, Byttner, Stefan, Davidsson, Anette, Kramberger, Milica G.,, Brendel, Matthias,, Lemstra, Afina W.,, Garibotto, Valentina, Byttner, Stefan,, Garibotto, Valentina,, Camacho, Valle,, Vandenberghe, Rik, Berckel, Bart N M van, Morbelli, Silvia, Martínez-Sanchis, Begoña,, Nobili, Flavio,, Etminani, Kobra,, Davidsson, Anette,, Alzheimer’s Disease Neuroimaging Initiative, Bauckneht, Matteo,, Rominger, Axel,, Soliman, Amira, Pilotto, Andrea,, Chang, Jose R, van Berckel, Bart N.M., Trost, Maja,, van Berckel, Bart N. M., Rominger, Axel, Ressner, Marcus, Brendel, Matthias, Padovani, Alessandro, Trost, Maja, Pilotto, Andrea, Soliman, Amira,, Bruffaerts, Rose, Mart\uednez-Sanchis, Bego\uf1a, Agudelo-Cifuentes, Marc,, Berckel, Bart N. M. van, Universitat Autònoma de Barcelona, Frisoni, Giovanni B, Stegeran, Roxana   +68 more
core   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

APOE4 rat model of Alzheimer’s disease: sex differences, genetic risk and diet

BMC Neuroscience
The strongest genetic risk factor for Alzheimer’s disease (AD) is the ε4 allele of apolipoprotein E (ApoE ε4). A high fat diet also adds to the risk of dementia and AD.
Bradley Colarusso, Richard Ortiz, Julian Yeboah, Arnold Chang, Megha Gupta, Praveen Kulkarni, Craig F. Ferris   +6 more
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Active inference and the two-step task

Scientific Reports, 2022
Sequential decision problems distill important challenges frequently faced by humans. Through repeated interactions with an uncertain world, unknown statistics need to be learned while balancing exploration and exploitation.
Sam Gijsen, Miro Grundei, Felix Blankenburg   +2 more
doaj   +1 more source

Alterations in somatosensory, visual and auditory pathways in amyotrophic lateral sclerosis: an under-recognised facet of ALS

Journal of Integrative Neuroscience, 2022
Background: While amyotrophic lateral sclerosis (ALS) is widely recognised as a multi-network disorder with extensive frontotemporaland cerebellar involvement, sensory dysfunction is relatively under evaluated.
Rangariroyashe H. Chipika, Grainne Mulkerrin, Aizuri Murad, Jasmin Lope, Orla Hardiman, Peter Bede   +5 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Kinematic parameters obtained with the ArmeoSpring for upper-limb assessment after stroke: a reliability and learning effect study for guiding parameter use

Journal of NeuroEngineering and Rehabilitation, 2020
Background After stroke, kinematic measures obtained with non-robotic and robotic devices are highly recommended to precisely quantify the sensorimotor impairments of the upper-extremity and select the most relevant therapeutic strategies.
Nabila Brihmat, Isabelle Loubinoux, Evelyne Castel-Lacanal, Philippe Marque, David Gasq   +4 more
doaj   +1 more source

A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis

npj Digital Medicine, 2023
Modern management of MS targets No Evidence of Disease Activity (NEDA): no clinical relapses, no magnetic resonance imaging (MRI) disease activity and no disability worsening.
Michael Barnett, Dongang Wang, Heidi Beadnall, Antje Bischof, David Brunacci, Helmut Butzkueven, J. William L. Brown, Mariano Cabezas, Tilak Das, Tej Dugal, Daniel Guilfoyle, Alexander Klistorner, Stephen Krieger, Kain Kyle, Linda Ly, Lynette Masters, Andy Shieh, Zihao Tang, Anneke van der Walt, Kayla Ward, Heinz Wiendl, Geng Zhan, Robert Zivadinov, Yael Barnett, Chenyu Wang   +24 more
doaj   +1 more source