Results 61 to 70 of about 399,982 (260)

Neuroimaging for acute ischemic stroke: current challenges [PDF]

, 2014
Over the last decade, neuroimaging methods have been refined to improve clinical decisions regarding acute stroke treatment. Computed tomography and magnetic resonance imaging are routinely used to rule out intracerebral haemorrhage or other ...
Wegener, Susanne
core   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Dynamic causal modelling of immune heterogeneity

Scientific Reports, 2021
An interesting inference drawn by some COVID-19 epidemiological models is that there exists a proportion of the population who are not susceptible to infection—even at the start of the current pandemic.
Thomas Parr, Anjali Bhat, Peter Zeidman, Aimee Goel, Alexander J. Billig, Rosalyn Moran, Karl J. Friston   +6 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Perceptual experience in somatosensory temporal discrimination is indexed by a mid-latency fronto-central ERP difference

Scientific Reports
The neural correlates of conscious somatosensory perception are usually investigated using threshold detection tasks. However, it is largely unclear how other aspects of conscious somatosensory experience, such as localization, discrimination, and ...
Jona Förster, Till Nierhaus, Pia Schröder, Felix Blankenburg   +3 more
doaj   +1 more source

Neuroimaging in Essential Tremor

, 2013
Essential tremor (ET) is the most common movement disorder and one of the most frequent neurological disorders. The pathophysiological mechanisms responsible for generating the action tremors are poorly understood, and the diagnosis remains predominantly
Fatta B. Nahab, Corneliu C. Luca, Luca, Corneliu C, Nahab, Fatta B   +3 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

A survey-based, quasi-experimental study assessing a high-cannabidiol suppository for menstrual-related pain and discomfort

npj Women's Health
The endocannabinoid system is involved in gynecological functions, with cannabidiol (CBD) demonstrating promise for alleviating menstrual-related symptoms.
M. Kathryn Dahlgren, Rosemary T. Smith, Deniz Kosereisoglu, Kelly A. Sagar, Ashley M. Lambros, Celine El-Abboud, Staci A. Gruber   +6 more
doaj   +1 more source

QuNex - An integrative platform for reproducible neuroimaging analytics

, 2023
Introduction: Neuroimaging technology has experienced explosive growth and transformed the study of neural mechanisms across health and disease.
Kraljič, Aleksij, Matkovič, Andraž, Ji, Jie Lisa, Winkler, Anderson, Purg, Nina, Warrington, Shaun, Murray, John D, Zerbi, Valerio, Helmer, Markus, Repovš, Grega, Coalson, Timothy S, Sotiropoulos, Stamatios N, Anticevic, Alan, Demšar, Jure, Pan, Lining, Glasser, Matthew F, Tamayo, Zailyn, Harms, Michael P, Fonteneau, Clara   +18 more
core   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source