Results 51 to 60 of about 390,558 (314)

Developmental changes in brain structure and function following exposure to oral LSD during adolescence

Scientific Reports
LSD is a hallucinogen with complex neurobiological and behavioral effects. Underlying these effects are changes in brain neuroplasticity. This is the first study to follow the developmental changes in brain structure and function following LSD exposure ...
Lila Harris-Blum, Zachary Smith, Richard J. Ortiz, Deepti Athreya, Arnold Chang, Praveen P. Kulkarni, Craig F. Ferris   +6 more
doaj   +1 more source

Kinematic parameters obtained with the ArmeoSpring for upper-limb assessment after stroke: a reliability and learning effect study for guiding parameter use

Journal of NeuroEngineering and Rehabilitation, 2020
Background After stroke, kinematic measures obtained with non-robotic and robotic devices are highly recommended to precisely quantify the sensorimotor impairments of the upper-extremity and select the most relevant therapeutic strategies.
Nabila Brihmat, Isabelle Loubinoux, Evelyne Castel-Lacanal, Philippe Marque, David Gasq   +4 more
doaj   +1 more source

Alterations in somatosensory, visual and auditory pathways in amyotrophic lateral sclerosis: an under-recognised facet of ALS

Journal of Integrative Neuroscience, 2022
Background: While amyotrophic lateral sclerosis (ALS) is widely recognised as a multi-network disorder with extensive frontotemporaland cerebellar involvement, sensory dysfunction is relatively under evaluated.
Rangariroyashe H. Chipika, Grainne Mulkerrin, Aizuri Murad, Jasmin Lope, Orla Hardiman, Peter Bede   +5 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Active inference and the two-step task

Scientific Reports, 2022
Sequential decision problems distill important challenges frequently faced by humans. Through repeated interactions with an uncertain world, unknown statistics need to be learned while balancing exploration and exploitation.
Sam Gijsen, Miro Grundei, Felix Blankenburg   +2 more
doaj   +1 more source

Adopting transfer learning for neuroimaging : a comparative analysis with a custom 3D convolution neural network model [PDF]

, 2022
: Background In recent years, neuroimaging with deep learning (DL) algorithms have made remarkable advances in the diagnosis of neurodegenerative disorders.
Martínez-Sanchis, Begoña, Aarsland, Dag,, Bauckneht, Matteo, Ochoa-Figueroa, Miguel, Kramberger, Milica G, Frisoni, Giovanni, Nicastro, Nicolas,, Ochoa-Figueroa, Miguel,, Etminani, Kobra, Camacho, Valle, Chincarini, Andrea, Agudelo-Cifuentes, Marc, Lemstra, Afina W, Stegeran, Roxana,, Berckel, Bart N.M.van,, Chang, Jose R., Nobili, Flavio, Frisoni, Giovanni B.,, Chincarini, Andrea,, Vandenberghe, Rik,, Kramberger, Milica G., Lemstra, Afina W., Morbelli, Silvia,, Padovani, Alessandro,, Aarsland, Dag, Ressner, Marcus,, Frisoni, Giovanni B., Bruffaerts, Rose,, Chang, Jose R.,, Nicastro, Nicolas, Byttner, Stefan, Davidsson, Anette, Kramberger, Milica G.,, Brendel, Matthias,, Lemstra, Afina W.,, Garibotto, Valentina, Byttner, Stefan,, Garibotto, Valentina,, Camacho, Valle,, Vandenberghe, Rik, Berckel, Bart N M van, Morbelli, Silvia, Martínez-Sanchis, Begoña,, Nobili, Flavio,, Etminani, Kobra,, Davidsson, Anette,, Alzheimer’s Disease Neuroimaging Initiative, Bauckneht, Matteo,, Rominger, Axel,, Soliman, Amira, Pilotto, Andrea,, Chang, Jose R, van Berckel, Bart N.M., Trost, Maja,, van Berckel, Bart N. M., Rominger, Axel, Ressner, Marcus, Brendel, Matthias, Padovani, Alessandro, Trost, Maja, Pilotto, Andrea, Soliman, Amira,, Bruffaerts, Rose, Mart\uednez-Sanchis, Bego\uf1a, Agudelo-Cifuentes, Marc,, Berckel, Bart N. M. van, Universitat Autònoma de Barcelona, Frisoni, Giovanni B, Stegeran, Roxana   +68 more
core   +2 more sources

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Association of Specific Leg Muscle Strength and Motor Features in Parkinson’s Disease

Parkinson's Disease
Background. Postural instability and gait difficulties (PIGD) are a significant cause of falls, mobility loss, and lower quality of life in Parkinson’s disease (PD).
Chatkaew Pongmala, Chernkhuan Stonsaovapak, Austin Luker, Alexis Griggs, Miriam van Emde Boas, Jacob M. Haus, Nicolaas I. Bohnen   +6 more
doaj   +1 more source

Reliability in adolescent fMRI within two years – a comparison of three tasks

Scientific Reports, 2017
Longitudinal developmental fMRI studies just recently began to focus on within-subject reliability using the intraclass coefficient (ICC). It remains largely unclear which degree of reliability can be achieved in developmental studies and whether this ...
Nora C. Vetter, Julius Steding, Sarah Jurk, Stephan Ripke, Eva Mennigen, Michael N. Smolka   +5 more
doaj   +1 more source

Integrative Hedonic and Homeostatic Food Intake Regulation by the Central Nervous System: Insights from Neuroimaging

, 2022
Food intake regulation in humans is a complex process controlled by the dynamic interaction of homeostatic and hedonic systems. Homeostatic regulation is controlled by appetitive signals from the gut, adipose tissue, and the vagus nerve, while conscious ...
Alejandro Campos, John D. Port, Andres Acosta   +2 more
core   +1 more source