Results 51 to 60 of about 658,358 (310)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

APOE4 rat model of Alzheimer’s disease: sex differences, genetic risk and diet

BMC Neuroscience
The strongest genetic risk factor for Alzheimer’s disease (AD) is the ε4 allele of apolipoprotein E (ApoE ε4). A high fat diet also adds to the risk of dementia and AD.
Bradley Colarusso, Richard Ortiz, Julian Yeboah, Arnold Chang, Megha Gupta, Praveen Kulkarni, Craig F. Ferris   +6 more
doaj   +1 more source

The promises and perils of the neuroscience of creativity. [PDF]

, 2013
Our ability to think creatively is one of the factors that generates excitement in our lives as it introduces novelty and opens up new possibilities to our awareness which in turn lead to developments in a variety of fields from science and technology to
Abraham, AG
core   +1 more source

Neuroimaging in Narcolepsy [PDF]

Sleep Medicine, 2010
Narcolepsy is a chronic neurological disorder, has no specific cause, and is characterized by excessive daytime sleepiness and uncontrollable sleep attacks. In case of strong emotions such as laughter, anger or joy, a cataplexy (sudden loss of muscle tone, lasting for a short period of time) may occur (1, 2).
Hakyemez, BAHATTİN, Bican, AYLİN, Alper, E., Ozkol, V., Algin, O., Bora, I.   +5 more
openaire   +6 more sources

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Active inference and the two-step task

Scientific Reports, 2022
Sequential decision problems distill important challenges frequently faced by humans. Through repeated interactions with an uncertain world, unknown statistics need to be learned while balancing exploration and exploitation.
Sam Gijsen, Miro Grundei, Felix Blankenburg   +2 more
doaj   +1 more source

Alterations in somatosensory, visual and auditory pathways in amyotrophic lateral sclerosis: an under-recognised facet of ALS

Journal of Integrative Neuroscience, 2022
Background: While amyotrophic lateral sclerosis (ALS) is widely recognised as a multi-network disorder with extensive frontotemporaland cerebellar involvement, sensory dysfunction is relatively under evaluated.
Rangariroyashe H. Chipika, Grainne Mulkerrin, Aizuri Murad, Jasmin Lope, Orla Hardiman, Peter Bede   +5 more
doaj   +1 more source

How can neuroscience contribute to moral philosophy, psychology and education based on Aristotelian virtue ethics? [PDF]

, 2016
The present essay discusses the relationship between moral philosophy, psychology and education based on virtue ethics, contemporary neuroscience, and how neuroscientific methods can contribute to studies of moral virtue and character. First, the present
Han, Hyemin
core   +2 more sources

Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda

NeuroImage: Clinical, 2021
Highlights • 1st Neuroimaging Workgroup Meeting in Functional Neurological Disorder (FND).• Underscores the importance of FND cohort characterization in brain imaging research.• Details methodological approaches taken in FND neuroimaging research to date.
D. Perez, T. Nicholson, A. Asadi-Pooya, I. Bègue, M. Butler, A. Carson, A. David, Q. Deeley, I. Díez, M. Edwards, A. Espay, J. Gelauff, M. Hallett, S. Horovitz, Johannes Jungilligens, R. Kanaan, M. Tijssen, K. Kozlowska, K. LaFaver, W. LaFrance, S. Lidstone, R. Marapin, Carine W Maurer, Mandana Modirrousta, A. Reinders, Petr Sojka, J. Staab, J. Stone, J. Szaflarski, S. Aybek   +29 more
semanticscholar   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source