Results 81 to 90 of about 515,093 (330)

Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García, H. Stephan Goedee, Leonard H. van den Berg, Boudewijn T. H. M. Sleutjes   +3 more
wiley   +1 more source

Differences in selectivity to natural images in early visual areas (V1–V3)

Scientific Reports, 2017
High-level regions of the ventral visual pathway respond more to intact objects compared to scrambled objects. The aim of this study was to determine if this selectivity for objects emerges at an earlier stage of processing.
David D. Coggan, Luke A. Allen, Oliver R. H. Farrar, Andre D. Gouws, Antony B. Morland, Daniel H. Baker, Timothy J. Andrews   +6 more
doaj   +1 more source

Neural correlates of cognitive intervention in persons at risk of developing Alzheimer's disease. [PDF]

, 2014
Cognitive training is an emergent approach that has begun to receive increased attention in recent years as a non-pharmacological, cost-effective intervention for Alzheimer's disease (AD).
Hosseini, SM Hadi, Kesler, Shelli R, Kramer, Joel H   +2 more
core   +1 more source

Bottom-up retinotopic organization supports top-down mental imagery [PDF]

, 2013
Finding a path between locations is a routine task in daily life. Mental navigation is often used to plan a route to a destination that is not visible from the current location. We first used functional magnetic resonance imaging (fMRI) and surface-based
Huang, R.-S., Sereno, Martin I.
core   +2 more sources

Functional Characterization and Pathogenicity Classification of PRRT2 Splice Variants in PRRT2‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu, Yu‐Lan Chen, Wan‐Bing Sun, Hong‐Fu Li, Zhi‐Ying Wu, Dian‐Fu Chen   +5 more
wiley   +1 more source

Perceptual experience in somatosensory temporal discrimination is indexed by a mid-latency fronto-central ERP difference

Scientific Reports
The neural correlates of conscious somatosensory perception are usually investigated using threshold detection tasks. However, it is largely unclear how other aspects of conscious somatosensory experience, such as localization, discrimination, and ...
Jona Förster, Till Nierhaus, Pia Schröder, Felix Blankenburg   +3 more
doaj   +1 more source

Speeding up Permutation Testing in Neuroimaging [PDF]

, 2015
Multiple hypothesis testing is a significant problem in nearly all neuroimaging studies. In order to correct for this phenomena, we require a reliable estimate of the Family-Wise Error Rate (FWER).
Hinrichs, Chris, Ithapu, Vamsi K, Johnson, Sterling C, Singh, Vikas, Sun, Qinyuan   +4 more
core  

Moyamoya Disease and the Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo, Jeong‐Yong Shin, Rugyeom Lee, Jiwon Cheon, Ji Hun Kim, Doeun Kim, Jae‐Kyung Won, In‐Hwan Oh, Yunjong Lee, Tae‐Beom Ahn   +9 more
wiley   +1 more source

A survey-based, quasi-experimental study assessing a high-cannabidiol suppository for menstrual-related pain and discomfort

npj Women's Health
The endocannabinoid system is involved in gynecological functions, with cannabidiol (CBD) demonstrating promise for alleviating menstrual-related symptoms.
M. Kathryn Dahlgren, Rosemary T. Smith, Deniz Kosereisoglu, Kelly A. Sagar, Ashley M. Lambros, Celine El-Abboud, Staci A. Gruber   +6 more
doaj   +1 more source

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism [PDF]

, 2013
BTBR T+tf/J (BTBR) mice display prominent behavioural deficits analogous to the defining symptoms of autism, a feature that has prompted a widespread use of the model in preclinical autism research.
A Gozzi, A Gozzi, A Gozzi, A Gozzi, A Gozzi, AA Turk, AC Stanfield, AE Dorr, Alberto Galbusera, Alessandro Gozzi, Allan V. Kalueff, Angelo Bifone, AY Hardan, AY Hardan, B Avants, BA Babineau, BB Avants, BB Avants, BB Avants, BU Meye, D Badaruddin, D Wahlsten, D Wahlsten, E Anagnostou, F Tovar-Moll, G Zaharchuk, H Ito, H Utsunomiya, J Ashburner, J Ellegood, JL Silverman, JL Silverman, JL Silverman, JL Whitwell, JM Mountz, JP Lerch, JP Lerch, KL Hyde, L Ferrari, L Ferrari, LK Paul, LK Paul, Luca Dodero, M Magnuson, M Sasaki, M Wohr, M Yang, M Yang, M Yang, M Zilbovicius, MA Just, Maria Luisa Scattoni, Mario Damiano, ME Vissers, ML Scattoni, ML Senjem, MM Haznedar, MM Haznedar, MS George, N Boddaert, N Hadjikhani, O Devinsky, R Adolphs, R Via E, RG Gonzalez, RJ Zatorre, S Mori, S Schobel, S Shen, SM Smith, Sotirios A. Tsaftsaris, SR Das, SS Moy, SS Moy, T Ohnishi, T Ren, TW Frazier, VJ Bolivar, WS Brown   +78 more
core   +3 more sources