Lentivirus Infection Causes Neuroinflammation and Neuronal Injury in Dorsal Root Ganglia: Pathogenic Effects of STAT-1 and Inducible Nitric Oxide Synthase [PDF]
, 2005 Yu Zhu +7 more
openalex +1 more source
Advanced Science, EarlyView.This work proposes a new mechanism for the regulation of LDs metabolism by ANXA7/PPARγ. ANXA7 can interact with PPARγ to promote its stability. ANXA7 activation promotes PPARγ nuclear translocation, thus promoting LDs formation and interaction with mitochondria by promoting PLIN5 expression.
Lu Chen +6 more
wiley +1 more source
Neuroinflammation and Neurodegeneration
, 2016 Pathophysiological processes of neurodegenerative diseases are not clearly defined. However, an important body of evidence points toward the role of various inflamma‐ tory processes. The microglial cell is the main representative of the immune system in the central nervous system (CNS).
Inelia Morales +3 more
openaire +3 more sources
Reducing Cerebral Microvascular Amyloid-β Protein Deposition Diminishes Regional Neuroinflammation in Vasculotropic Mutant Amyloid Precursor Protein Transgenic Mice [PDF]
, 2005 Jianting Miao +5 more
openalex +1 more source
Advanced Science, EarlyView.Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan +6 more
wiley +1 more source
Alcohol Abuse Enhances Neuroinflammation and Impairs Immune Responses in an Animal Model of Human Immunodeficiency Virus-1 Encephalitis [PDF]
, 2006 Raghava Potula +9 more
openalex +1 more source
Endothelial PD‐1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development
Advanced Science, EarlyView.Vascular endothelial cells are fundamental for angiogenesis and brain development. This study reveals that endothelial programmed cell death 1 (PD‐1) is critical for cerebral angiogenesis and blood brain barrier (BBB) maturation. It also mediates interaction with oligodendrocyte precursor cells (OPCs), modulating OPCs differentiation and myelination ...
Tingting He +7 more
wiley +1 more source
Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease [PDF]
, 2006 R. Lee Mosley +7 more
openalex +1 more source
Advanced Science, EarlyView.This study uses Caenorhabditis elegans to assess the activity of amphetamine‐type stimulants (ATS) and their analogs. The research highlights the roles of dopamine and serotonin pathways, distinguishes chiral forms of ATS, and identifies structure‐activity relationships. These findings provide a rapid and cost‐effective model for evaluating the effects
Yuanpeng Li +3 more
wiley +1 more source
Cell morphologies in the nervous system: Glia steal the limelight
Journal of Comparative Neurology, Volume 531, Issue 3, Page 338-343, February 2023., 2023 Diversity of digitally reconstructed glia (astrocytes, oligodendrocytes, microglia, and other types) freely available for download and reuse at NeuroMorpho.Org in terms of experimental provenance, animal species, anatomical region, cell type, tracing platform, and more.
Giorgio A. Ascoli
wiley +1 more source