Results 241 to 250 of about 212,554 (299)

Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice

Annals of Neurology, EarlyView.
Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier   +19 more
wiley   +1 more source

Targeting glial cell pyroptosis and neuroinflammation in post-stroke depression: from molecular mechanisms to therapeutic strategies. [PDF]

Front Immunol
Li X, Wei Y, She Y, Long W, Zhou S, Shi M, Wang Z, Zou X, Mao J, Xiao X, Shi H, Qin D.   +11 more
europepmc   +1 more source

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

Annals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez, Cyril Pottier, Aleksandra Beric, Daniel Western, Muhammad Ali, Carlos Cruchaga   +5 more
wiley   +1 more source

Correction: Inhibition of astrocyte signaling leads to sex-specific changes in microglia phenotypes in a diet-based model of cerebral small vessel disease. [PDF]

J Neuroinflammation
Gollihue JL, Aung KZ, Rogers CB, Galopin LB, Wright NA, Sompol P, Weekman EM, Katsumata Y, Morganti JM, Norris CM.   +9 more
europepmc   +1 more source

Lidocaine Injection into the Rat Dorsal Root Ganglion Causes Neuroinflammation

, 2009
Livia Puljak, Sanja Lovrić Kojundžić, Quinn H. Hogan, Damir Sapunar   +3 more
openalex   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Shared Neuroinflammatory Mechanisms Across Dementia Types: An Integrative Review. [PDF]

Int J Mol Sci
Thangaleela S, Ali A, Tandoro Y, Wang CK.   +3 more
europepmc   +1 more source

Anti-inflammatory effects of cannabidiol in early stages of neuroinflammation induced by high-fat diet in cerebral cortex of rats

Aleksandra Opęchowska, Kacper Robert Karpiuk, Andrii Zahorodnii, Ewa Harasim‐Symbor, Adrian Chabowski, Karolina Konstantynowicz-Nowicka   +5 more
openalex   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Fucoidan Extracted from <i>Fucus vesiculosus</i> Ameliorates Colitis-Associated Neuroinflammation and Anxiety-like Behavior in Adult C57BL/6 Mice. [PDF]

Mar Drugs
Song X, Li N, Li X, Yuan B, Zhang X, Li S, Yang X, Qi B, Yin S, Li C, Huang Y, Zhang B, Guo Y, Zhao J, Wu X.   +14 more
europepmc   +1 more source