Results 321 to 330 of about 240,724 (351)
Some of the next articles are maybe not open access.
Galectins and Neuroinflammation
2014Galectins, β-galactoside-binding lectins, play multiple roles in the regulation of immune and inflammatory responses. The major galectins expressed in the CNS are galectins 1, 3, 4, 8, and 9. Under normal physiological conditions, galectins maintain CNS homeostasis by participating in neuronal myelination, neuronal stem cell proliferation, and apical ...
Hung-Lin Chen +3 more
openaire +3 more sources
Current Opinion in Neurology, 2012
Publisher Summary The central nervous system's (CNS) innate immune response involves intricate signaling circuitry and cellular networks. The primary cells involved in neuroinflammation are the microglia that actively survey the brain microenvironment and upon activation, serve as the resident macrophages in the CNS.
Monica K. Ertel +3 more
openaire +4 more sources
Publisher Summary The central nervous system's (CNS) innate immune response involves intricate signaling circuitry and cellular networks. The primary cells involved in neuroinflammation are the microglia that actively survey the brain microenvironment and upon activation, serve as the resident macrophages in the CNS.
Monica K. Ertel +3 more
openaire +4 more sources
Cytokine networks in neuroinflammation
Nature Reviews Immunology, 2016Cytokines provide cells with the ability to communicate with one another and orchestrate complex multicellular behaviour. There is an emerging understanding of the role that cytokines play in normal homeostatic tissue function and how dysregulation of these cytokine networks is associated with pathological conditions.
Becher, Burkhard +2 more
openaire +4 more sources
Developmental neuroinflammation and schizophrenia [PDF]
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2013 There is increasing interest in and evidence for altered immune factors in the etiology and pathophysiology of schizophrenia. Stimulated by various epidemiological findings reporting elevated risk of schizophrenia following prenatal exposure to infection, one line of current research aims to explore the potential contribution of immune-mediated ...
openaire +3 more sources
Science Signaling, 2017
The soluble form of the innate immune receptor TREM2 promotes microglial survival and inflammatory responses in the brain.
openaire +3 more sources
The soluble form of the innate immune receptor TREM2 promotes microglial survival and inflammatory responses in the brain.
openaire +3 more sources
Ketogenic diet and Neuroinflammation
Epilepsy Research, 2020AbstractThe high-fat, low-carbohydrate ketogenic diet (KD) is an established and proven treatment for pharmacoresistant epilepsy. Recently, the KD has been validated as a treatment option for some inflammation-induced epileptic encephalopathies. Given the broad neuroprotective properties of the KD in various experimental models of neurologic disorders,
Sookyong Koh +2 more
openaire +3 more sources
Neuroinflammation and Schizophrenia
Current Psychiatry Reports, 2019There are longstanding, intriguing findings of immune dysfunction in schizophrenia. These findings span peripheral immune markers, especially cytokine abnormalities.This review describes recent genetic and immune marker studies and emergent treatment studies. Collectively, this provides a synthesis and current appraisal of the neuroimmune hypothesis of
openaire +2 more sources
Molecular Neurobiology
Neuroinflammation is an immune response in the central nervous system and poses a significant threat to human health. Studies have shown that the receptor serine/threonine protein kinase family (RIPK) family, a popular research target in inflammation, has been shown to play an essential role in neuroinflammation.
Yue Xu +5 more
openaire +2 more sources
Neuroinflammation is an immune response in the central nervous system and poses a significant threat to human health. Studies have shown that the receptor serine/threonine protein kinase family (RIPK) family, a popular research target in inflammation, has been shown to play an essential role in neuroinflammation.
Yue Xu +5 more
openaire +2 more sources
In vivo imaging of neuroinflammation
European Neuropsychopharmacology, 2002We briefly outline the rationale for employing positron emission tomography (PET), using the ligand [11C](R)-PK11195, the binding site for which is highly expressed by activated microglia, in order (a) to detect in vivo neuroinflammatory changes occurring in a variety of brain diseases and at different disease stages and (b) to monitor the progression ...
Annachiara Cagnin +4 more
openaire +4 more sources