Results 11 to 20 of about 3,097,745 (309)

The immunogenetics of neurological disease [PDF]

Immunology, 2017
SummaryGenes encoding antigen‐presenting molecules within the human major histocompatibility complex (MHC) account for the highest component of genetic risk for many neurological diseases, such as multiple sclerosis, neuromyelitis optica, Parkinson's disease, Alzheimer's disease, schizophrenia, myasthenia gravis and amyotrophic lateral sclerosis ...
Maneesh K. Misra, Vincent Damotte, Jill A. Hollenbach   +2 more
openaire   +2 more sources

Pseudo Chiari with holocord syringomyelia secondary to cerebrospinal fluid hypotension. Case report

Interdisciplinary Neurosurgery, 2022
Introduction: Pseudo-Chiari malformation results from caudal displacement of brain structures secondary to cerebrospinal fluid (CSF) hypotension. Some case reports in the syringomyelia literature are associated with a pseudo-Chiari malformation.
Emiliano Lorefice, Sebastián J.M Giovannini, Andrés Cervio, Santiago Condomí Alcorta, Rubén Mormandi   +4 more
doaj   +1 more source

Sterol auto-oxidation adversely affects human motor neuron viability and is a neuropathological feature of amyotrophic lateral sclerosis

Scientific Reports, 2021
Aberrant cholesterol homeostasis is implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disease that is due to motor neuron (MN) death. Cellular toxicity from excess cholesterol is averted when it is enzymatically
James C. Dodge, Jinlong Yu, S. Pablo Sardi, Lamya S. Shihabuddin   +3 more
doaj   +1 more source

COVID-19 pandemic and individuals with severe mental illness: A comparative study of community mental health centers' early experiences in COVID-19 pandemic (tur)

Klinik Psikiyatri Dergisi, 2022
INTRODUCTION: In this study, we aimed to determine the effects of the early phase of the COVID-19 pandemic on the services in Community Mental Health Centers (CMHCs) and on the patients followed up by the CMHC. In this direction, the clinical data of the
Nazife Gamze Usta Sağlam, Engin Emrem Beştepe, Filiz İzci, İpek Sarıkaya, Haluk Usta, Fatih Baz   +5 more
doaj   +1 more source

Functional connectivity of the language area in migraine: a preliminary classification model

BMC Neurology, 2023
Background Migraine is a complex disorder characterized by debilitating headaches. Despite its prevalence, its pathophysiology remains unknown, with subsequent gaps in diagnosis and treatment.
Chen Gou, Shuangfeng Yang, Qianmei Hou, Peter Rudder, Onur Tanglay, Isabella Young, Tingting Peng, Weiwei He, Liuyi Yang, Karol Osipowicz, Stephane Doyen, Negar Mansouri, Michael E. Sughrue, Xiaoming Wang   +13 more
doaj   +1 more source

Curcumin and neurological diseases [PDF]

Nutritional Neuroscience, 2020
Objectives: The beneficial effects of many substances have been discovered because of regular dietary consumption. This is also the case with curcumin, whose effects have been known for more than 4,000 years in Eastern countries such as China and India. A curcumin-rich diet has been known to counteract many human diseases, including cancer and diabetes,
Raffaella Adami, Daniele Bottai
openaire   +2 more sources

Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]

, 2012
Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
MacLean, L., Peter G. E. Kennedy (126080), MacLean Lorna, Sternberg, J.M., Sternberg, Jeremy M, Peter G E Kennedy, Hansotto Reiber (126078), Sternberg Jeremy M., Reiber, H., Kennedy Peter G. E., Jeremy M Sternberg, Kennedy, Peter G E, Lorna MacLean, MacLean, Lorna, Lorna MacLean (126077), Jeremy M. Sternberg (126082), Reiber Hansotto, Kennedy, P.G.E., Reiber, Hansotto, Hansotto Reiber   +19 more
core   +1 more source

Response to Telemedicine Visits From Patients With Parkinsonism During the COVID-19 Pandemic on Postvisit Surveys

Journal of Patient Experience, 2021
Parkinson’s disease and parkinsonism are common chronic neurodegenerative disorders that tend to affect older adults and cause physical and sometimes cognitive limitations.
Wissam Deeb MD, Christopher W Hess MD, Noheli Gamez MHA, Bhavana Patel DO, Kathryn Moore MD, Melissa J Armstrong MD, MSc   +5 more
doaj   +1 more source

Blood levels of Glial Fibrillary Acidic Protein (GFAP) in patients with neurological diseases [PDF]

, 2013
Background and Purpose: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Niessner, Marion, Robert Brunkhorst, Brunkhorst, Robert, Helmuth Steinmetz, Steinmetz, Helmuth, Marion Niessner, Mayer, Christoph, Christian Foerch, Pfeilschifter, Waltraud, Christoph A Mayer, Förch, Christian, Waltraud Pfeilschifter   +11 more
core   +2 more sources

Biomarker and genomic analyses reveal molecular signatures of non-cardioembolic ischemic stroke

Signal Transduction and Targeted Therapy, 2023
Acute ischemic stroke (AIS) is a major cause of disability and mortality worldwide. Non-cardioembolic ischemic stroke (NCIS), which constitutes the majority of AIS cases, is highly heterogeneous, thus requiring precision medicine treatments.
Lingling Ding, Yu Liu, Xia Meng, Yong Jiang, Jinxi Lin, Si Cheng, Zhe Xu, Xingquan Zhao, Hao Li, Yongjun Wang, Zixiao Li   +10 more
doaj   +1 more source