Results 111 to 120 of about 1,108,914 (332)

Differentiation of neuropsychological features between posterior cortical atrophy and early onset Alzheimer’s disease

BMC Neurology, 2018
Background Posterior cortical atrophy (PCA) is a group of clinical syndromes characterized by visuospatial and visuoperceptual impairment, with memory relatively preserved. Although PCA is pathologically almost identical to Alzheimer’s disease (AD), they
Jieying Li, Liyong Wu, Yi Tang, Aihong Zhou, Fen Wang, Yi Xing, Jianping Jia   +6 more
doaj   +1 more source

The effect of changes in society, economy and public health on the disease burden of neurological, mental and substance use disorders: a global longitudinal study [PDF]

, 2019
Yankun Sun, Yao Yao, Yanping Bao, Yan Sun, Le Shi, Jie Shi, Lin Lü   +6 more
openalex   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Targeted Control of Gene Expression Using CRISPR-Associated Endoribonucleases

Cells
CRISPR-associated endoribonucleases (Cas RNases) cleave single-stranded RNA in a highly sequence-specific manner by recognizing and binding to short RNA sequences known as direct repeats (DRs).
Sagar J. Parikh, Heather M. Terron, Luke A. Burgard, Derek S. Maranan, Dylan D. Butler, Abigail Wiseman, Frank M. LaFerla, Shelley Lane, Malcolm A. Leissring   +8 more
doaj   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

IL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation

Journal of Neuroinflammation, 2018
Background Brain inflammation including increases in inflammatory cytokines such as IL-1β is widely believed to contribute to the pathophysiology of Alzheimer’s disease.
Liqi Tong, G. Aleph Prieto, Carl W. Cotman   +2 more
doaj   +1 more source

Out of the shadows : services for persons with epilepsy in Malta [PDF]

, 2000
Epilepsy is the most common neurological disorder in clinical practice and it is a generic term used to define a variety of seizure disorders. A seizure is a disturbance in the electrical activity of the brain. There are more than 20 different epilepsies
Mifsud, Janet
core  

Plasma Signature of Neurological Disease in the Monogenetic Disorder Niemann-Pick Type C [PDF]

, 2014
Md. Suhail Alam†, Michelle Getz, Sue Y. Yi, Jeffrey L. Kurkewich, Innocent Safeukui, Kasturi Haldar   +5 more
openalex   +1 more source

Rapid exome sequencing in PICU patients with new-onset metabolic or neurological disorders [PDF]

, 2020
Abigail S. Carey, John P. Schacht, Christine Umandap, David Fasel, Chunhua Weng, Joshua Cappell, Wendy K. Chung, Steven G. Kernie   +7 more
openalex   +1 more source