Results 101 to 110 of about 2,302,356 (314)
Depression and neurological disorders
Neurosciences, 2009 Depression is the most common psychiatric disorder in neurological disorders such as epilepsy, multiple sclerosis, stroke, and Parkinsons disease. It is associated with reduction of quality of life, functional impairment, and higher mortality. The diagnosis of depression in neurological disorders is difficult because of the overlapping symptoms ...
openaire +2 more sources
, 2017 BACKGROUND: Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation.
GBD 2015 Neurological Disorders Collaborator Group +5 more
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Navigating Neurological Disorders: A Comprehensive Guide to Diagnosis and Treatment
, 2023 Navigating Neurological Disorders: A Comprehensive Guide to Diagnosis and ...
Mumta Lulwani
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FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Neurosteroids and neurological disorders
The Korean Journal of Physiology & PharmacologyNeurosteroids play an important role as endogenous neuromodulators that are locally produced in the central nervous system and rapidly change the excitability of neurons and the activation of microglial cells and astrocytes. Here we review the mechanisms of synthesis, metabolism, and actions of neurosteroids in the central nervous system. Neurosteroids
Park, Gi Wan +4 more
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Retinal Vascular Changes in Acute Neurological Disorders
, 2019 There are two acute neurological disorders for which retinal vascular changes are of substantial importance: headache and cerebral ...
Beau Bruce, MD, PhD
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Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Wrangling RNA: Antisense oligonucleotides for neurological disorders [PDF]
, 2019 Effective treatment of spinal muscular atrophy with antisense oligonucleotide therapy opens the door to treating other neurological disorders with this ...
core +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source