Results 81 to 90 of about 2,302,356 (314)

Plasma platelet-derived growth factor receptor-β decrease correlates with blood-brain barrier damage in Alzheimer’s disease

Molecular Neurodegeneration
Background The blood-brain barrier (BBB) damage is frequently observed in Alzheimer’s disease (AD). However, it remains unclear whether plasma platelet-derived growth factor receptor-β (PDGFRβ) level is related to BBB damage and how it correlates with AD
Jieyin Li, Anqi Li, Chenghui Ye, Laihong Zhang, Mingxing Jiang, Guoyu Lan, Fernando Gonzalez-Ortiz, Jie Yang, Yalin Zhu, Yue Cai, Pan Sun, Lin Liu, Zhengbo He, Xin Zhou, Lili Fang, Yiying Wang, Zhen Liu, Kaj Blennow, Shaohua Ma, Xuhui Chen, Dai Shi, Tengfei Guo   +21 more
doaj   +1 more source

Modulation of functionally localized right insular cortex activity using real-time fMRI-based neurofeedback

Frontiers in Human Neuroscience, 2013
The capacity for subjects to learn to volitionally control localized brain activity using neurofeedback is actively being investigated. We aimed to investigate the ability of healthy volunteers to quickly learn to use visual feedback during real-time ...
Brian D Berman, Brian D Berman, Silvina G Horovitz, Mark eHallett   +3 more
doaj   +1 more source

Neurological Disorders

, 2016
The generation and functional integration of adult-born neurons in the hippocampus and subventricular zone suggest an important mechanism of neural plasticity in the adult brain.
S.-Y. Yau, Yau, SY, B.W. Man Lau, Po, KT, So, KF, K.-F. So, Man Lau, BW, K.-T. Po   +7 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Handbook of animal models in neurological disorders

, 2022
Handbook of Animal Models in Neurological Disorders will better readers’ understanding of a large variety of animal models and their applicability in studying a number of neurological disorders.
Preedy, Victor, Patel, Vinood, Martin, Colin   +2 more
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Causal relationships between type 1 diabetes mellitus and Alzheimer’s disease and Parkinson’s disease: a bidirectional two-sample Mendelian randomization study

European Journal of Medical Research
Background Previous compelling evidence suggests an association between Type 2 diabetes (T2D) and neurodegenerative diseases. However, it remains uncertain whether Type 1 diabetes mellitus (T1DM) exerts a causal influence on the risk of Alzheimer's ...
Chaofan Geng, Ke Meng, Bo Zhao, Xiaoduo Liu, Yi Tang   +4 more
doaj   +1 more source

Neurological and psychiatric disorders in psoriasis

, 2018
Psoriasis used to be known as a skin disorder; however, it can now be considered as a systemic disease with the involvement of multiple organs. Neurological and psychiatric disorders are some of the associated problems that can be observed in patients ...
Man Amanat, Mona Salehi, Nima Rezaei
core   +1 more source

Association of pregnancy loss with other autoimmune neurological disorders.

, 2022
Association of pregnancy loss with other autoimmune neurological disorders.
David Westergaard (4856410), Øjvind Lidegaard (558709), Anders Pretzmann Mikkelsen (12329578), Henriette Svarre Nielsen (8292186), Pia Egerup (820241), Astrid Marie Kolte (12329581)   +5 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source