Results 111 to 120 of about 2,206,438 (308)

Current Options and Future Directions in Immune Therapy for Glioblastoma

Frontiers in Oncology, 2018
Glioblastoma is in need of innovative treatment approaches. Immune therapy for cancer refers to the use of the body's immune system to target malignant cells in the body.
John Lynes, John Lynes, Victoria Sanchez, Gifty Dominah, Anthony Nwankwo, Edjah Nduom   +5 more
doaj   +1 more source

Neurology and renal disorders [PDF]

Clinical Medicine, 2007
The kidney and the nervous system have close interactions under both physiological and pathological states Systemic disorders like diabetes, hypertension, vasculitudes and genetic disorders can affect both the nervous system and the kidney Awareness and early recognition of conditions such as thrombocytopenic purpura and osmotic demyelination syndromes
openaire   +2 more sources

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Neurological sleep disorders

, 2023
This review summarises the current knowledge of neurological sleep disorders. These disorders are frequent and involve a number of serious diseases associated with complications or precede other serious brain diseases.
Jennum, Poul Jørgen, Asah, Cresta, Frandsen, Rune   +2 more
core   +1 more source

Chinese neuroimmunological disease (NIDBase) cohort study: cohort profile

BMJ Open
Purpose The Chinese neuroimmunological disease database (NIDBase) cohort was established to explore genetic and environmental risk factors, clinical features, multi-omics data and prognostic biomarkers.
Zheng Liu, Jiangwei Xia, Siqi Chen, Ming Lin, Junwei Hao, Dawei Li, Yinan Zhao, Jinming Han, Yuqi Tang, Zhandong Qiu, Huiqing Dong, Mengyao Zhang, Teng Chen, Shishuang Ruan, Qiujia Wang, Yi Men, Ruiping Gao, Hanyue Zheng, Jiajian Li, Yuan Qi, Yingtao Wang, Xixi Yang   +21 more
doaj   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Targeted Control of Gene Expression Using CRISPR-Associated Endoribonucleases

Cells
CRISPR-associated endoribonucleases (Cas RNases) cleave single-stranded RNA in a highly sequence-specific manner by recognizing and binding to short RNA sequences known as direct repeats (DRs).
Sagar J. Parikh, Heather M. Terron, Luke A. Burgard, Derek S. Maranan, Dylan D. Butler, Abigail Wiseman, Frank M. LaFerla, Shelley Lane, Malcolm A. Leissring   +8 more
doaj   +1 more source

Neurological manifestations and implications of COVID-19 pandemic.

, 2020
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and rapidly spread worldwide, with a vast majority of confirmed cases presenting with respiratory symptoms.
Fischer, Urs Martin, Chan, Amanda C, Zand, Ramin, Voumvourakis, Konstantinos I, Schellinger, Peter D, Kelly, Peter, Alexandrov, Andrei V, Köhrmann, Martin, Caso, Valeria, Palaiodimou, Lina, Cordonnier, Charlotte, Sharma, Vijay K, Grigoriadis, Nikolaos, Katsanos, Aristeidis H, Sarraj, Amrou, Tsiodras, Sotirios, Tsivgoulis, Georgios, Molina, Carlos   +17 more
core   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source