BIOCHEMISTRY AND NEUROLOGY: METABOLIC DISORDERS IN DISEASES OF THE CENTRAL NERVOUS SYSTEM
The central nervous system (CNS) is one of the most metabolically active systems in the human body. Proper neuronal function depends on continuous energy production, balanced neurotransmitter metabolism, mitochondrial integrity, and redox homeostasis. Metabolic disturbances can impair neuronal communication, accelerate neurodegeneration, and contributeTuychieva Mashhuraxon Alisher qizi +1 more
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Inflammatory and Autoimmune Central Nervous System Diseases and the Neurology of Sepsis
2016Headache is considered to be a nearly universal experience. Approximately 98% of the population will experience some form of headache in a lifetime. The number of migraineurs worldwide is approximately 1 billion, and nearly 1 in every 4 households in the United States has at least one family member who experiences migraine.
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The role of secretory phospholipase A₂ in the central nervous system and neurological diseases.
Molecular neurobiology, 2014Secretory phospholipase A2 (sPLA2s) are small secreted proteins (14-18 kDa) and require submillimolar levels of Ca(2+) for liberating arachidonic acid from cell membrane lipids. In addition to the enzymatic function, sPLA2 can exert various biological responses by binding to specific receptors.
Tatsurou, Yagami +2 more
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ACSL4-Mediated Ferroptosis and Its Potential Role in Central Nervous System Diseases and Injuries
International Journal of Molecular Sciences, 2023Chengliang Luo
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S100-mediated signal transduction in the nervous system and neurological diseases.
Cellular and molecular biology (Noisy-le-Grand, France), 2006This article presents new information regarding the complement/level of S100 family members expressed in the brain and reviews the contribution of brain S100 family members to nervous system function and disease. A total of ten S100 family members are reported in the literature to be expressed in brain -S100A1, S100A2, S100A4, S100A5, S100A6, S100A10 ...
D B, Zimmer +3 more
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The glymphatic system: implications for drugs for central nervous system diseases
Nature Reviews Drug Discovery, 2022Maiken Nedergaard +2 more
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Virtual Screening-Based Drug Development for the Treatment of Nervous System Diseases
Current Neuropharmacology, 2023Wei-Jiang Zhao
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Targeting sialylation to treat central nervous system diseases
Trends in Pharmacological Sciences, 2021Jan Lunemann, Harald Neumann
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Cancer and the Nervous System: The Neurological Manifestations of Systemic Malignant Disease
Mayo Clinic Proceedings, 1985openaire +1 more source

