Traditional neuromodulation using rigid electrodes has been limited by low precision, large stimulating currents, and the risk of tissue damage. In this work, we developed a biocompatible flexible electrode array that allows for both neural recording of spike firings and high‐precision, low‐threshold stimulation for neuromodulation.
Yifei Ye+16 more
wiley +1 more source
Neuromodulation for Lower Urinary Tract Dysfunction – An Update [PDF]
Zahid Hussain, Simon Harrison
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Neuromodulation of short-term synaptic dynamics examined in a mechanistic model based on kinetics of calcium currents [PDF]
Lian Zhou, Shunbing Zhao, Farzan Nadim
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Fermented soybean extract (FSE) at 50 mg/L has the potential to mitigate lead (Pb) toxicity (5 mg/L) observed in the zebrafish model. This study offers insights into food intervention in toxicology. ABSTRACT This study investigated the potential of fermented soybean extract (FSE) as an alternative therapy for lead (Pb) toxicity, without chelation side ...
Siok‐Geok Chong, Intan Safinar Ismail
wiley +1 more source
Brain-machine interactive neuromodulation research tool with edge AI computing
Closed-loop neuromodulation with intelligence methods has shown great potentials in providing novel neuro-technology for treating neurological and psychiatric diseases.
Yan Li+11 more
doaj
The Effect of Montage on the Analgesic Response to Percutaneous Neuromodulation Therapy
Paul F. White+5 more
openalex +1 more source
Sacral neuromodulation: factors that affect cure rates for urge incontinence [PDF]
Caroline Barranco
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Genetically‐targeted control of the spinal cord and peripheral nervous system
Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano+3 more
wiley +1 more source
1303: A Randomized Prospective Study Comparing the Efficacy of Two Test Stimulation Techniques for Sacral Neuromodulation in Urge Incontinent Women > 55 Years of Age [PDF]
Kristy M. Borawski+3 more
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MR‐Guidance of Gene Therapy for Brain Diseases: Moving From Palliative Treatment to Cures
ABSTRACT Regulatory bodies in the U.S. and Europe recently approved a gene therapy for aromatic L‐amino acid decarboxylase (AADC) deficiency, a rare neurologic disorder where a genetic mutation prevents dopamine production in the brain. Affected children fail to develop normal motor and cognitive functions.
Dalton H. Bermudez+2 more
wiley +1 more source