Results 111 to 120 of about 3,849 (222)

Action of dopamine as inhibitory neuromodulator in jellyfish synapse

, 2017
Dopamine (DA) acts on swimming motor neurons (SMNs) of Polyorchis penicillatus as an inhibitory neurotransmitter by hyperpolarizing their membrane potentials, which results from the activation of voltage-sensitive potassium channels mediated through a D2-
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core  

IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses.

, 2017
Interleukin-17 (IL-17) is a major pro-inflammatory cytokine: it mediates responses to pathogens or tissue damage, and drives autoimmune diseases. Little is known about its role in the nervous system.
de Bono, M., Sheng, M., Laurent, P., Changchun Chen, Chen, Changchun,, Itakura, Eisuke, Laurent, Patrick, Chen, Changchun Chen, C, Fenk, Lorenz L.A., Geoffrey M. Nelson, Fenk, Lorenz A., de Bono, Mario, Butcher, R., Nelson, Geoffrey M, Rebecca A. Butcher, Mario de Bono, Chen, C., Nelson, G., Ramanujan S. Hegde, Fenk, L., Sheng, Ming, Hegde, Ramanujan S., Hegde, Ramanujan S, Butcher, Rebecca A, Patrick Laurent, Lorenz A. Fenk, Ming Sheng, Itakura, E., Hegde, R., Nelson, Geoffrey M., Eisuke Itakura, Butcher, Rebecca A.   +31 more
core   +1 more source

Exacerbated ATP transmission in the carotid body is linked to glomus cell expansion in spontaneously hypertensive rats

The Journal of Physiology, EarlyView.
Abstract figure legend Exacerbated ATP signalling in the carotid body (CB) of spontaneously hypertensive rats (SHRs) arises from expansion of the chemosensory glomus cell compartment and reduced extracellular ATP metabolism, leading to increased purinergic drive.
Igor S. A. Felippe, Audrys Pauza, Olivia M. S. Gold, Xin Shen, Fernanda Brognara, Rosanna Roberts Nonu, Dylan K. Pen, Aabharika Bose, Emma N. Bardsley, Anna P. Ponnampalam, Davi J. A. Moraes, Julian F. R. Paton   +11 more
wiley   +1 more source

RTP004 Peptide Binds to Botulinum Neurotoxin, Increases Cell Surface Binding, and Enhances Cellular SNAP-25 Cleavage

Toxins
DaxibotulinumtoxinA for injection (DAXI) is a botulinum neurotoxin (BoNT) drug product comprising the 150 kDa pure BoNT/A1 as the drug substance formulated with a proprietary stabilizing excipient, RTP004.
Andre F. Batista, Ratnesh Singh, Frank Lee, Shaoqiu Zhuo, Dmitri Leonoudakis, Conor J. Gallagher   +5 more
doaj   +1 more source

Galanin – a neuromodulator involved in the cardiovascular homeostasis

, 2012
Galanin is a 29 amino acid peptide acting as a neuromodulator in the central and peripheral nervous systems. It infl uences a variety of the central nervous system, functions, including food intake regulation, learning and memory, neuroendocrine control ...
Kawecki, Damian, Rybczyk, Renata, Jochem, Jerzy, Krawiec, Adam   +3 more
core  

The endogenous cannabinoid system gates plasticity of tonic GABA inhibition

The Journal of Physiology, EarlyView.
Abstract figure legend Postsynaptic depolarisation and increases in intracellular Ca2+ ([Ca2+]i) trigger the synthesis of endocannabinoids (eCBs), which are hypothesised to enhance tonic GABAergic inhibition via two primary pathways. In the proposed autocrine mechanism, eCBs activate postsynaptic somatodendritic or mitochondrial CB1 receptors ...
Roberto Colangeli, Fiorenzo Conti
wiley   +1 more source

Neuromodulator timing regulates adult cortical plasticity via the synaptic eligibility trace

Brain Stimulation
Introduction: Learning-induced cortical reorganization is facilitated by neuromodulator release. However, the precise temporal relationship between neuromodulator release and neural activity required to induce plasticity is not well understood. In single
Brendan M. Williams, Michael S. Borland, Tanya T. Danaphongse, Lasya Pasapula, Jayant K. Rajagopal, Seth A. Hays, Crystal T. Engineer   +6 more
doaj   +1 more source

Chronic pruritus treated with alendronate in bilateral striopallidodentate calcinosis associated with an SLC20A2 gene mutation

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Adrien Boyard, Florian Stéphan, Boris Chaumette, Mathilde Moreau, Laure Bleton, Nicolas Hornez, Steeve Genestet, Jérémy Betrand, Amélie Bourhis, Morgane Le Bon‐Jégo, Thierry Bienvenu, Camille Verebi, Laurent Misery   +12 more
wiley   +1 more source

Noise‐induced reduction and early recovery of superior paraolivary nucleus sound‐offset responses

The Journal of Physiology, EarlyView.
Abstract figure legend Acoustic over‐exposure transiently disrupts auditory temporal processing in mouse superior paraolivary nucleus neurons. In control conditions, neurons exhibit robust sound‐offset (OFF) responses, which are abolished immediately following noise trauma, indicating impaired temporal encoding.
Mihai Stancu, Ezhilarasan Rajaram, Joseph A. Kroeger, Benedikt Grothe, Conny Kopp‐Scheinpflug   +4 more
wiley   +1 more source

Neuromodulation for Epilepsy

The Neurodiagnostic Journal
Epilepsy surgery encompasses a wide range of procedures aimed at reducing or eliminating seizures. In these procedures, there are opportunities to employ intraoperative neurophysiology to map the epileptic focus and accurately identify functional areas of the brain.
Nathan J. Pertsch, Kazuki Sakakura, Sepehr Sani, Jay Shils   +3 more
openaire   +4 more sources