Results 91 to 100 of about 3,849 (222)
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Frontiers in Pharmacology, 2014 Neuromodulators have profound effects on behavior, but the dynamics of their intracellular effectors has remained unclear. Most neuromodulators exert their function via G-protein-coupled receptors (GPCRs).
Yao eChen +6 more
doaj +1 more source
Synchronization in the suprachiasmatic nucleus through gap junction and neuromodulator coupling
, 2019 A better understanding in the biological clock is important to help reduce stress on shift workers. Moreover, in the field of medication it will allow for more effective treatments as certain types of medication are more effective when applied at certain
Heerkens Thijssen, Oscar (author)
core
Dynorphin acts as a neuromodulator to inhibit itch in the dorsal horn of the spinal cord [PDF]
, 2014 Menthol and other counterstimuli relieve itch, resulting in an antipruritic state that persists for minutes to hours. However, the neural basis for this effect is unclear, and the underlying neuromodulatory mechanisms are unknown.
Kardon, Adam P. +19 more
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira +3 more
wiley +1 more source
Checks and balances in neuromodulation
Frontiers in Behavioral Neuroscience, 2010 Neuromodulators such as monoamines and peptides play important roles in activating and reconfiguring neural networks to allow behavioral flexibility. While the net effects of a neuromodulator change the network in a particular direction, careful studies ...
Ronald M Harris-Warrick +1 more
doaj +1 more source
Pain Comorbidities with Attention Deficit: A Narrative Review of Clinical and Preclinical Research
Journal of Pain ResearchHong-Bin Liang,1,2 Wan-You He,2 Yan-Ping Liu,3 Han-Bing Wang1,2 1Graduate School of Guangdong Medical University, Zhanjiang, Guangdong Province, People’s Republic of China; 2Department of Anesthesiology, The First People’s Hospital of Foshan, Foshan ...
Liang HB, He WY, Liu YP, Wang HB
doaj
The Effect of Micro-Focused Ultrasound Treatment on Intradermal Botulinum Toxin Type A Injection
ToxinsBotulinum toxin type A (BoNT-A) injection and micro-focused ultrasound with visualization (MFU-V) are becoming increasingly popular for various esthetic conditions.
Sarawin Harnchoowong +2 more
doaj +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.The first Australian guidance document on the assessment and management of idiopathic gastroparesis (IGP) reconceptualises IGP as a sensorimotor disorder. It proposes a novel multidisciplinary treatment algorithm and 20 high‐consensus recommendations, addressing common overlapping disorders, and providing clear guidance on associated disordered eating ...
Trina Kellar +11 more
wiley +1 more source
Frequency-dependent signal transmission and modulation by neuromodulators
Frontiers in Neuroscience, 2008 The brain uses a strategy of labor division, which may allow it to accomplish more elaborate and complicated tasks, but in turn, imposes a requirement for central control to integrate information among different brain areas.
Hiroshi T Ito, Erin M Schuman
doaj +1 more source