Results 21 to 30 of about 3,849 (222)
Neuromodulator release in neurons requires two functionally redundant calcium sensors [PDF]
, 2021 Neuropeptides and neurotrophic factors secreted from dense core vesicles (DCVs) control many brain functions, but the calcium sensors that trigger their secretion remain unknown. Here, we show that in mouse hippocampal neurons, DCV fusion is strongly and
van Westen, Rhodé +6 more
core +1 more source
Frontiers in Immunology, 2023 Nicotinamide adenine dinucleotide (NAD) is a substrate of adenosine diphosphate (ADP)-ribosyl cyclase and is catalyzed to cyclic ADP-ribose (cADPR) by CD38 and/or CD157.
Maria Gerasimenko, Haruhiro Higashida
doaj +1 more source
Circadian rhythmogenesis from neuromodulator- and molecular clock-mediated network mixed feedback [PDF]
, 2023 peer reviewedThe suprachiasmatic nucleus (SCN) is a subset of neurons in charge of timekeeping circadian phenomena. As a network, it is capable of maintaining periodic activity with stable phase-locking patterns in spite of heterogeneous nodes.
Franci, Alessio, Juarez-Alvarez, Omar
core +1 more source
Escape steering by cholecystokinin peptidergic signaling
Cell Reports, 2022 Summary: Escape is an evolutionarily conserved and essential avoidance response. Considered to be innate, most studies on escape responses focused on hard-wired circuits.
Lili Chen +15 more
doaj +1 more source
Corelease of acetylcholine and GABA from cholinergic forebrain neurons
eLife, 2015 Neurotransmitter corelease is emerging as a common theme of central neuromodulatory systems. Though corelease of glutamate or GABA with acetylcholine has been reported within the cholinergic system, the full extent is unknown.
Arpiar Saunders +2 more
doaj +1 more source
Neurotransmitters and Neuromodulators [PDF]
Acta geneticae medicae et gemellologiae, 1974 In the central nervous system, besides the neurotransmitters, the occurrence of substances which modify neuronal excitability has been proposed. Since their effect is a matter of modulating neuronal responsiveness, these substances may be called neuromodulators.Examples of neurotransmitters or putative neurotransmitters in the central nervous system ...
openaire +1 more source
Neurochemistry of Visual Attention
Frontiers in Neuroscience, 2021 Visual attention is the cognitive process that mediates the selection of important information from the environment. This selection is usually controlled by bottom-up and top-down attentional biasing.
Denise Elfriede Liesa Lockhofen +1 more
doaj +1 more source
Neuromodulation of Attention [PDF]
Neuron, 2018 Attention is critical to high-level cognition and attention deficits are a hallmark of neurologic and neuropsychiatric disorders. Although years of research indicates that distinct neuromodulators influence attentional control, a mechanistic account that traverses levels of analysis (cells, circuits, behavior) is missing.
Thiele, Alexander, Bellgrove, Mark A.
openaire +2 more sources
An Introduction to Predictive Processing Models of Perception and Decision‐Making
Topics in Cognitive Science, EarlyView., 2023 Abstract The predictive processing framework includes a broad set of ideas, which might be articulated and developed in a variety of ways, concerning how the brain may leverage predictive models when implementing perception, cognition, decision‐making, and motor control.
Mark Sprevak, Ryan Smith
wiley +1 more source
Dopamine: The Neuromodulator of Long-Term Synaptic Plasticity, Reward and Movement Control [PDF]
, 2021 Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions including motor control, modulation of affective and emotional states, reward mechanisms, reinforcement of behavior, and selected higher cognitive functions. Dysfunction
Davide Viggiano +4 more
core +2 more sources