Results 61 to 70 of about 3,849 (222)

A 32-ch Neuromodulator with redundant Voltage Monitors avoiding Blocking Capacitors

open access: yes, 2022
Neural recording and modulation has evolved rapidly in recent years. Closed-loop neuromodulation systems have been successfully demonstrated for the treatment of Parkinson‘s disease and epilepsy.
Reich, Stefan   +5 more
core   +1 more source

Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS

open access: yesAdvanced Science, EarlyView.
A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun   +10 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

State dependent vagus nerve stimulation for targeted plasticity therapy: challenges and considerations

open access: yesFrontiers in Control Engineering
Targeted plasticity therapy (TPT) utilizes vagus nerve stimulation (VNS) to promote improvements in function following neurological injury and disease.
Bharadwaj Nandakumar   +18 more
doaj   +1 more source

Cellular and neurochemical basis of sleep stages in the thalamocortical network

open access: yeseLife, 2016
The link between the combined action of neuromodulators in the brain and global brain states remains a mystery. In this study, using biophysically realistic models of the thalamocortical network, we identified the critical intrinsic and synaptic ...
Giri P Krishnan   +7 more
doaj   +1 more source

Giant Conductivity Modulation and Chemical Neuromodulation via Proton‐Electron Coupling in a Hydrogen‐Bonded Coordination Polymer

open access: yesAdvanced Science, EarlyView.
A “de‐doping” strategy positions mixed protonic–electronic conductors (MPECs) as adaptive neuromorphic platforms with dynamically tunable transport. Co‐BAND achieves giant conductivity modulation (>106) and chemically tunable synaptic plasticity. Analogous to biological neuromodulation, solvent vapors dynamically reprogram the device's learning rules ...
Kwangmin Park   +10 more
wiley   +1 more source

Taurine as an Essential Neuromodulator during Perinatal Cortical Development

open access: yes, 2017
A variety of experimental studies demonstrated that neurotransmitters are an important factor for the development of the central nervous system, affecting neurodevelopmental events like neurogenesis, neuronal migration, programmed cell death, and ...
Werner Kilb, Atsuo Fukuda
core   +1 more source

The 9th International RASopathies Symposium

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel   +41 more
wiley   +1 more source

The Serotonergic System and Its Role in Thermoregulation

open access: yesPhysiologia
Serotonin (5-hydroxytryptamine—5-HT) is an important neurotransmitter that exerts a remarkably large array of biological roles in the central nervous system and at the body level. It is involved in generating emotions, being a natural mood stabilizer; it
Andrei-Ionuţ Negoiţă   +3 more
doaj   +1 more source

Models of Acetylcholine and Dopamine Signals Differentially Improve Neural Representations

open access: yesFrontiers in Computational Neuroscience, 2017
Biological and artificial neural networks (ANNs) represent input signals as patterns of neural activity. In biology, neuromodulators can trigger important reorganizations of these neural representations.
Raphaël Holca-Lamarre   +5 more
doaj   +1 more source

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