Results 271 to 280 of about 95,633 (353)

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Mapping Dental Care for Children and Adolescents With Rare Diseases: A Brazilian Multicentre Study

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To describe the landscape of dental care provided by specialised centres for children and adolescents with rare diseases (RDs) in the state of Minas Gerais, southeastern Brazil. Methods A retrospective cross‐sectional study was conducted involving individuals aged 0–18 years with a confirmed diagnosis of a RD who received care at ...
Heloisa Vieira Prado   +21 more
wiley   +1 more source

Expressive language and social communication abilities in children with spinal muscular atrophy type 1

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To investigate parent‐reported expressive language and social communication abilities in children with spinal muscular atrophy type 1 (SMA1) treated with disease‐modifying therapies. Method This was a cross‐sectional feasibility study performed at the Dubowitz Neuromuscular Centre, London (UK), and the Centro Clinico Nemo Pediatrico, Rome (
Chiara Brusa   +19 more
wiley   +1 more source

Comfort and Usability of Digital Versus Conventional Custom‐Fit Mouthguards: A Randomized Clinical Trial

open access: yesDental Traumatology, EarlyView.
ABSTRACT Background/Objectives The use of mouthguards protects teeth and the supporting tissues against impacts. Digital impressions and 3D‐printed models can reduce manufacturing steps and minimize discomfort. This study evaluated the fit, comfort, and usability of custom‐made mouthguards, obtained by conventional and digital workflow, in amateur ...
Maryuri Macías Bautista   +8 more
wiley   +1 more source

Effect of sugammadex titration versus manufacturer's recommendation for reversal of rocuronium-induced neuromuscular block: a prospective, randomized, controlled trial. [PDF]

open access: yesBMC Anesthesiol
Gao L   +14 more
europepmc   +1 more source

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