Results 281 to 290 of about 92,981 (315)
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International Anesthesiology Clinics, 1988
Clearly, many aspects of the action of neuromuscular blockers remain poorly understood at the molecular level. In the case of competitive blockers, blockade of EPPs by competitive binding to the ACh receptor site accounts for the most clinically important aspect of blockade.
Joe Henry Steinbach +1 more
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Clearly, many aspects of the action of neuromuscular blockers remain poorly understood at the molecular level. In the case of competitive blockers, blockade of EPPs by competitive binding to the ACh receptor site accounts for the most clinically important aspect of blockade.
Joe Henry Steinbach +1 more
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The future of neuromuscular blocking agents
Current Opinion in Anaesthesiology, 2020Purpose of review The present review provides a summary of the literature on recent development of new neuromuscular blocking agents and presents clinically well established and new reversal agents. Recent findings Anesthesiologists are still waiting for the ideal neuromuscular ...
Christiane G. Stäuble, Manfred Blobner
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Neuromuscular blocking agents and reversal agents
Anaesthesia & Intensive Care Medicine, 2011Abstract The neuromuscular junction consists of the motor nerve terminal, the synaptic cleft and post-synaptic nicotinic receptors on the motor end-plate of striated muscle. Neuromuscular blocking drugs are categorized into depolarizing and non-depolarizing agents.
Khorat Farooq +3 more
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Veterinary Clinics of North America: Equine Practice, 2002
In summary, with proper vigilance, neuromuscular blocking agents can be used safely in anesthetized equine patients to optimize conditions for certain surgical procedures. By appropriate use of neuromuscular monitoring techniques and reversal agents, residual blockade and muscle weakness should be avoided, allowing the horse to recover to standing ...
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In summary, with proper vigilance, neuromuscular blocking agents can be used safely in anesthetized equine patients to optimize conditions for certain surgical procedures. By appropriate use of neuromuscular monitoring techniques and reversal agents, residual blockade and muscle weakness should be avoided, allowing the horse to recover to standing ...
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American Journal of Nursing, 1997
O nene afternoon at her 150bed community hospital, Marcia Czabo, RN, a new nurse manager for the intensive care unit, was conducting a quality improvement survey of stock medications in the medication room. She quickly made two alarming discoveries: She found pancuronium located in the stock box where heparin flush solutions should have been, and ...
Robert Guanci, Linda L. Lilley
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O nene afternoon at her 150bed community hospital, Marcia Czabo, RN, a new nurse manager for the intensive care unit, was conducting a quality improvement survey of stock medications in the medication room. She quickly made two alarming discoveries: She found pancuronium located in the stock box where heparin flush solutions should have been, and ...
Robert Guanci, Linda L. Lilley
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2010
Neuromuscular blocking agents have, perhaps, the most fascinating history among the drugs used in anesthesiology and intensive care. For centuries, South American aborigines had used curare to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle.1 These historical ...
Rafael Ortega +2 more
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Neuromuscular blocking agents have, perhaps, the most fascinating history among the drugs used in anesthesiology and intensive care. For centuries, South American aborigines had used curare to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle.1 These historical ...
Rafael Ortega +2 more
openaire +2 more sources
Critical Care Medicine, 1993
On logical grounds, the term “neuromuscular-blocking agent” might be applied to any drug, the primary action of which is to interrupt neuromuscular transmission. This chapter discusses those drugs of which the primary site of action is the postjunctional motor endplate cholinoceptors and drugs that are used as muscle relaxants in anaesthetic practice ...
Cheryl J. Williams, Pam Dulin
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On logical grounds, the term “neuromuscular-blocking agent” might be applied to any drug, the primary action of which is to interrupt neuromuscular transmission. This chapter discusses those drugs of which the primary site of action is the postjunctional motor endplate cholinoceptors and drugs that are used as muscle relaxants in anaesthetic practice ...
Cheryl J. Williams, Pam Dulin
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2016
Many drugs used for induction or maintenance of anaesthesia provide a degree of skeletal muscle relaxation, but in general this is only mild to moderate at a surgical plane of anaesthesia. This chapter looks at different ways to achieve more profound muscle relaxation, neuromuscular blocking agents (NMBAs) and their mechanism, monitoring the ...
Derek Flaherty, Adam Auckburally
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Many drugs used for induction or maintenance of anaesthesia provide a degree of skeletal muscle relaxation, but in general this is only mild to moderate at a surgical plane of anaesthesia. This chapter looks at different ways to achieve more profound muscle relaxation, neuromuscular blocking agents (NMBAs) and their mechanism, monitoring the ...
Derek Flaherty, Adam Auckburally
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2017
Neuromuscular blockade is used in the operating room and in the intensive care unit. While in the operating room, almost every patient undergoing general anesthesia receives neuromuscular blocking agents, in the intensive care unit setting, curarization is reserved only to some patients.
Bignami E., Saglietti F.
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Neuromuscular blockade is used in the operating room and in the intensive care unit. While in the operating room, almost every patient undergoing general anesthesia receives neuromuscular blocking agents, in the intensive care unit setting, curarization is reserved only to some patients.
Bignami E., Saglietti F.
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Neuromuscular Blocking Agents and Neuromuscular Diseases
2000Acquired neuromuscular diseases or congenital disorders either affect the neuromuscular transmission or the muscle itself. When the neuromuscular transmission is involved, two pathophysiological mechanisms must be distinguished: the abnormality of the nicotinic receptor at the endplate (myasthenia gravis, upregulation of the receptor) and the ...
Benoit Plaud, François Donati
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