Results 291 to 300 of about 92,981 (315)
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Neuromuscular blocking agents and reversal agents
Anaesthesia & Intensive Care Medicine, 2005Abstract The neuromuscular blocking agents in routine clinical use may be classed as depolarizing or nondepolarizing. Suxamethonium is the only example of the depolarizing group and is an agonist at the neuromuscular receptor. It has the most rapid onset and the shortest duration of action, though it has a number of important unwanted side-effects ...
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LITHIUM CARBONATE AND NEUROMUSCULAR BLOCKING AGENTS
Survey of Anesthesiology, 1977The effects of lithium carbonate on the responses to five neuromuscular blocking agents were evaluated in dogs anesthetized with halothane (1 per cent) and N2O (60 per cent) in O2. Latency (time from first twitch-height depression to maximal blockade), maximal twitch-height depression, and times to return to 50 per cent and 100 per cent control twitch ...
Gary E. Hill +2 more
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2012
The effect of different antiepileptic drugs on the pharmacokinetics of various neuromuscular blocking agents including atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium and vecuronium are described. Also, potential pharmacodynamic interactions are highlighted.
Philip N. Patsalos, Philip N. Patsalos
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The effect of different antiepileptic drugs on the pharmacokinetics of various neuromuscular blocking agents including atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium and vecuronium are described. Also, potential pharmacodynamic interactions are highlighted.
Philip N. Patsalos, Philip N. Patsalos
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Neuromuscular transmission: New concepts and agents
Journal of Critical Care, 2009Sugammadex is the first selective relaxant binding agent which was originally designed to reverse the steroidal NMB drug rocuronium. The results of recent studies demonstrate that sugammadex is effective for reversal of rocuronium and vecuronium-induced neuromuscular block without apparent side-effects.
Hans D. de Boer, Hans D. de Boer
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Journal of Pharmacy Practice, 1994
Neuromuscular blocking (NMB) agents are frequently used in the operating room (OR) as well as the intensive care units. The number of NMB agents available for use in these areas continues to increase. The clinician currently has 10 agents from which to choose, with another (rocuronium) soon to be available.
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Neuromuscular blocking (NMB) agents are frequently used in the operating room (OR) as well as the intensive care units. The number of NMB agents available for use in these areas continues to increase. The clinician currently has 10 agents from which to choose, with another (rocuronium) soon to be available.
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The history of neuromuscular blocking agents
Current Anaesthesia & Critical Care, 2000Abstract Muscle relaxants play an important role in anaesthesia. Although the paralysing effect of some Indian poisons had been originally described in the 16th century, the active alkaloids of curare were only discovered early in the 20th century. The paralysing effect was first used for clinical purposes outside anaesthesia and surgery in the 18th ...
Pollard, Brian, Booij, H. H D J
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The Danger With Neuromuscular Blocking Agents
Journal of Emergency Nursing, 2004Susan Paparella, Ches-mont Chapter, is Director for Consulting Services,Institute for Safe Medication Practices (ISMP*), Huntingdon Valley, Pa, and a member of ENA’s ED Safety Workgroup. For reprints, write: Susan Paparella, RN, MSN, 1800 Byberry Rd, Suite 800, Huntingdon Valley, PA 19006; E-mail: spaparella@ismp.org. J Emerg Nurs 2004;30:250-2.
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1990
In animal experiments succinylcholine increases ICP (Cottrell et al. 1983, Lanier et al. 1986). The increase in ICP is also observed after pre-treatment with thiopentone (Thiagarajah et al. 1988). In dogs subjected to succinylcholine injection, CBF increases within a few minutes and this hyperperfusion is accompanied by EEG activation (Mori et al. 1973,
Georg E. Cold, Jörn Bo Madsen
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In animal experiments succinylcholine increases ICP (Cottrell et al. 1983, Lanier et al. 1986). The increase in ICP is also observed after pre-treatment with thiopentone (Thiagarajah et al. 1988). In dogs subjected to succinylcholine injection, CBF increases within a few minutes and this hyperperfusion is accompanied by EEG activation (Mori et al. 1973,
Georg E. Cold, Jörn Bo Madsen
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Hypersensitivity Reactions to Neuromuscular Blocking Agents
Current Pharmaceutical Design, 2008Neuromuscular blocking agents are the leading drugs responsible for immediate hypersensitivity reactions during anaesthesia. Most hypersensitivity reactions represent IgE-mediated allergic reactions. Their incidence is estimated to be between 1 in 3,000 to 1 in 110,000 general anaesthetics. However striking variations have been reported among countries.
H. Bouaziz +9 more
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Disadvantages of Neuromuscular Blocking Agents
Veterinary Clinics of North America: Small Animal Practice, 1992Neuromuscular blocking agents have few indications and significant contraindications or problems associated with their use. The need for controlled ventilation and the difficulties of monitoring anesthetic depth when using neuromuscular blocking agents are overriding factors that mitigate against their routine use.
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