Results 151 to 160 of about 362,451 (418)
Emerging considerations in the reversal of neuromuscular blockade and residual block [PDF]
, 2008 Incomplete recovery following reversal of neuromuscular blockade can present as a clinical problem in surgical patients. Emerging pharmacologic solutions may prevent such adverse outcomes in the future.
CHRISTOPHER J. JANKOWSKI +2 more
core +2 more sources
Annals of Neurology, EarlyView.Objectives Rapid advances in transcriptomics have driven efforts to identify deregulated pathways in multiple sclerosis (MS) tissues, though many detected differentially expressed genes are likely false positives, with only a small fraction reflecting actual pathological events. Robust, integrative methods are essential for accurately understanding the
Gianmarco Abbadessa +11 more
wiley +1 more source
HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models
Annals of Neurology, EarlyView.Objective We aimed to characterize the phenotypic spectrum and functional consequences associated with variants in HCN2, encoding for the hyperpolarization‐activated cyclic nucleotide (HCN) gated channel 2. Methods GeneMatcher facilitated the recruitment of 21 individuals with HCN2 variants from 15 unrelated families, carrying HCN2 variants.
Clara Houdayer +52 more
wiley +1 more source
Maximum likelihood q-estimator reveals nonextensivity regulated by extracellular potassium in the mammalian neuromuscular junction [PDF]
arXiv, 2013 Recently, we demonstrated the existence of nonextensivity in neuromuscular transmission [Phys. Rev. E 84, 041925 (2011)]. In the present letter, we propose a general criterion based on the q-calculus foundations and nonextensive statistics to estimate the values for both scale factor and q-index using the maximum likelihood q-estimation method (MLqE ...
arxiv
The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Advanced NanoBiomed Research, EarlyView.Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He +11 more
wiley +1 more source
Multiple model adaptive control of neuromuscular blockade: Design guidelines and clinical cases [PDF]
, 2007 The high level of uncertainty of the dynamic response of patients subject to anaesthesia motivates the use of adaptive control methods. This paper proposes an approach based on Switched Multiple Model Adaptive Control (SMMAC) to tackle this problem in ...
Hugo Magalhães +4 more
core +1 more source
Advances in Therapy, 2017 IntroductionSustained deep neuromuscular blockade (NMB) during laparoscopic surgery may facilitate optimal surgical conditions. This exploratory study assessed whether deep NMB improves surgical conditions and, in doing so, allows use of lower ...
J. Rosenberg +10 more
semanticscholar +1 more source
Clinical Anatomy, EarlyView.ABSTRACT The orbicularis oculi muscle (OOc) is strongly associated with facial aging as its contraction causes the formation of crow's feet. Botulinum neurotoxin (BoNT) injection is a representative treatment targeting muscle. The aim of this study was to demonstrate the anatomical relationship between the OOc and the zygomaticus complex muscles, and ...
Jiong‐Zhen Piao +3 more
wiley +1 more source
Pre‐oviposition development of the brown anole (Anolis sagrei)
Developmental Dynamics, EarlyView.Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling +9 more
wiley +1 more source
Scientific Reports, 2017 The aim of this study is to evaluate the efficacy and safety of sugammadex for reversing neuromuscular blockade in pediatric patients. MEDLINE and other three Databases were searched.
Guangyu Liu +5 more
semanticscholar +1 more source