Results 191 to 200 of about 46,631 (307)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

The Role of Deep Neuromuscular Blockade and Sugammadex in Laparoscopic Hysterectomy: A Randomized Controlled Trial. [PDF]

J Clin Med
Terranova C, Schiavoni L, Plotti F, Costa F, Feole L, Rampello S, Ficarola F, Montera R, Guzzo F, Luvero D, Di Donato V, Mattei A, Angioli R, De Cicco Nardone C.   +13 more
europepmc   +1 more source

Cisatracurium in Acute Respiratory Distress Syndrome [PDF]

, 2014
Hill, John D, Howitt, Joshua R, Nauser, Trenton D   +2 more
core   +2 more sources

Ventilation Imaging of the Lung at 0.55T With Continuous Slice Cycling

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To propose and evaluate a novel method for pulmonary ventilation imaging, offering considerably improved SNR. Methods A continuous slice cycling (CSC) acquisition scheme is proposed to exclusively capture signal modulations from respiratory motion with increased SNR.
Andrea Leuthard, Grzegorz Bauman, Katrin E. Hostettler, Maurice Pradella, Oliver Bieri   +4 more
wiley   +1 more source

Assessment of Neuromuscular Blockade Depth Using Train-of-Four (TOF) Monitoring Following Rocuronium Extravasation. [PDF]

Cureus
Yoshioka K, Iwamoto T, Kawase H, Ishikawa S, Takeda Y.   +4 more
europepmc   +1 more source

Shear Wave Elastography to Assess Respiratory Muscle Function in Congenital Myopathies

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Respiratory muscle dysfunction is prevalent in congenital myopathies and often leads to respiratory failure. Ultrasound shear wave elastography (SWE) measures tissue elasticity and has been proposed as an alternative to invasive measures of respiratory muscle contractility.
J. L. M. van Doorn, D. Jans, C. L. de Korte, B. G. M. van Engelen, N. C. Voermans, N. van Alfen, C. A. C. Ottenheijm, D. Bachasson, J. Doorduin   +8 more
wiley   +1 more source

Sugammadex vs Neostigmine for Reversal of Neuromuscular Blockade and Association with Postoperative Atelectasis After Video-Assisted Thoracoscopic Surgery: A Propensity Score-Matched Cohort Study. [PDF]

Drug Des Devel Ther
Hung KC, Weng HL, Wu JY, Hsu CW, Yang CP, Lai YC, Chen IW.   +6 more
europepmc   +1 more source

Asynchrony Related to Mechanical Ventilation Exacerbates Diaphragm Dysfunction in a Mouse Model of Duchenne Muscular Dystrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims In dystrophic mice (mdx, a genetic homolog of Duchenne muscular dystrophy: DMD), previous studies showed that mechanical ventilation (MV) induces ventilator‐induced diaphragmatic dysfunction (VIDD). However, susceptibility to mechanical stress caused by asynchrony remains unknown.
Mohamad Yehya, Haikel Dridi, Eric Estève, Johan Moreau, Steven Reiken, Andrew R. Marks, Alain Lacampagne, Stefan Matecki   +7 more
wiley   +1 more source

Deep neuromuscular blockade improves surgical conditions during laparoendoscopic single-site (LESS) surgery for total hysterectomy and reduces postoperative pain: a randomized controlled trial. [PDF]

Perioper Med (Lond)
Shen Y, Hu J, Lv F, Yu C, Gong Y, Wang D, Zeng X.   +6 more
europepmc   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk, Michel Wyndaele, Ana Charrua, Christopher Fry, Paul Abrams, Gommert A. van Koeveringe, Anthony J. Kanai, Marcus J. Drake   +7 more
wiley   +1 more source