Results 221 to 230 of about 46,257 (309)

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Analgesia, Sedation, and Neuromuscular Blockade in Pediatric Severe Traumatic Brain Injury: Secondary Analysis of the "Approaches and Decisions in Acute Pediatric TBI Trial" (ADAPT). [PDF]

Neurocrit Care
Laws JC, Rakkar J, Buttram SDW, Wolf MS.
europepmc   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Relief of pain associated with spasticity in adult patients after treatment with onabotulinumtoxinA: Post hoc observational results from the ASPIRE study

PM&R, EarlyView.
Abstract Background Pain is often observed in patients with spasticity, but little is known about the relationship between pain and spasticity and the effectiveness of treating pain with botulinum toxins in these patients. Objective To explore onabotulinumtoxinA (onabotA) use and pain relief in patients with spasticity with pain at baseline.
Jörg Wissel, Cassandra List, Marc Schwartz, Mariana Nelson, Tiziana Musacchio, Esther Duarte   +5 more
wiley   +1 more source

Comparison of reversal of rocuronium-induced neuromuscular blockade with sugammadex under remimazolam versus propofol anesthesia: a randomized clinical trial. [PDF]

J Anesth
Kawasaki T, Fujimoto M, Hirata N.
europepmc   +1 more source

Botulinum toxin use in patients with neurological disorders: A U.S.‐based claims database analysis

PM&R, EarlyView.
Abstract Background and Objective Real‐world evidence describing long‐term persistency with botulinum toxin (BoNT) therapy is limited. We assessed treatment patterns and persistency with BoNT in clinical practice over 2 years. Design Retrospective, longitudinal, claims database analysis. Setting Medical claims data from the Merative MarketScan database
David M. Simpson, Jonathan Bouchard, Simon Page, Seth Goldfarb, Atul T. Patel   +4 more
wiley   +1 more source

Deep versus Moderate Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function: A Randomized Controlled Trial. [PDF]

Anesth Analg
Bijkerk V, Jacobs LMC, Rijnen WHC, Keijzer C, Warlé MC, Visser J.   +5 more
europepmc   +1 more source

Diagnostic Accuracy of Cough Frequency Monitors: A Systematic Review and Meta‐Analysis

Respirology, EarlyView.
ABSTRACT Background and Objective International guidelines emphasise the importance of objective cough assessment for evaluating therapeutic efficacy. Cough negatively impacts quality of life and generates high costs for healthcare systems. However, the accuracy of cough frequency monitors remains unclear.
Ana Lara Castro Rodrigues, Larisse Sousa Reis Passafaro, Daniele Oliveira dos Santos, Marcos Gontijo da Silva, Noé Mitterhofer Eiterer Ponce de Leon da Costa, Janne Marques Silveira, Arietta Spinou, Ada Clarice Gastaldi   +7 more
wiley   +1 more source

General Anesthesia Using Laryngeal Mask Airway Ventilation With Low-Dose Neuromuscular Blockade Is Safe and Effective for Patients Undergoing Hip Arthroscopy. [PDF]

Arthrosc Sports Med Rehabil
Jabara JT, Neuner JH, Vasanthan A, Aleshi P, Kinjo S, Wong SE, Zhang AL.   +6 more
europepmc   +1 more source

OSA Endotyping as Targets for Treatment. How Far Have We Come?

Respirology, EarlyView.
ABSTRACT Obstructive sleep apnoea (OSA) is highly prevalent and is associated with significant impairments in quality of life and comorbidity. The most common treatment employed is continuous positive airway pressure (CPAP), especially in moderate and severe cases.
Walter T. McNicholas, Sara Op de Beeck, Pasquale Tondo, Johan Verbraecken, Maria R. Bonsignore   +4 more
wiley   +1 more source