Results 281 to 290 of about 47,410 (348)

Transcriptional Diversity in Response to Aging Across Skeletal Muscles

open access: yesAging Cell, EarlyView.
We constructed transcriptional maps of 11 skeletal muscles from young and old mice, revealing age‐related tissue‐specific gene expression changes. Our findings highlight cellular composition shifts and new cell states in aged muscles, providing insights into muscle aging and potential therapeutic targets for age‐related muscle disorders. ABSTRACT Aging
Can Liu   +15 more
wiley   +1 more source

Fatal drug overdoses in healthcare workers: A thematic framework analysis of coroner reports

open access: yesAddiction, EarlyView.
Abstract Background and aims Healthcare workers face specific vulnerabilities for drug overdose due to their unique access to medications, clinical knowledge and work‐related stress. This study aimed to understand the characteristics of fatal overdoses in healthcare workers with a view to providing guidance for preventative strategies.
Thikra Algahtani   +6 more
wiley   +1 more source

Airway management in patients living with obesity: best practice recommendations from the Society for Obesity and Bariatric Anaesthesia

open access: yesAnaesthesia, EarlyView.
Summary Introduction Patients living with obesity present specific challenges for airway management. They have been overrepresented repeatedly in studies looking at complications associated with airway management. Whilst generic airway guidelines offer assistance, there are no evidence‐based guidelines specific to this group of patients to support safe
Andrew McKechnie   +7 more
wiley   +1 more source

Adjustment of positive end‐expiratory pressure based on body mass index during general anaesthesia: a randomised controlled trial*

open access: yesAnaesthesia, EarlyView.
Summary Introduction Lung‐protective ventilation is essential for preventing postoperative pulmonary complications. While maintaining a low driving pressure and optimising PEEP is of importance, the ideal strategy remains contentious. This study evaluated whether adjusting PEEP based on BMI, compared with standard PEEP, could reduce driving pressure ...
Helene Selpien   +9 more
wiley   +1 more source

Repetitive Grasping After Stroke Assisted by Functional Electrical Stimulation

open access: yesArtificial Organs, EarlyView.
To understand whether FES can be useful in assisting functional grasping after stroke, the following requirements were investigated: (i) producing sufficient force, (ii) sustaining this force for an adequate duration, (iii) successfully releasing the object, and (iv) monitoring the onset of muscle fatigue during repetitive grasping.
Chiara Höhler   +6 more
wiley   +1 more source

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