Artificial Organs, EarlyView.TESCS‐ABT induced neurophysiological changes in individuals with chronic complete SCI, however these did not consistently translate into functional improvements. These findings highlight the role of residual supraspinal connectivity and inform future research to optimise this neurotechnology for SCI rehabilitation and identify likely responders ...
E. L. McNicol +6 more
wiley +1 more source
Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial
BJU International, Volume 135, Issue 4, Page 638-647, April 2025.Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui +2 more
wiley +1 more source
Cerebellar defects are a primary pathology in mouse models of spinal muscular atrophy
Brain Pathology, EarlyView.Purkinje cell (PC) degeneration is localized to posterior lobules in the cerebellum, and rescue of survival motor neuron protein expression levels in motor neurons does not ameliorate this effect. Representative images of sagittal cerebellar sections stained with anti‐calbindin in the vermis and hemisphere at P12 for wild type, ChATCre+ rescue (Rescue),
Nicholas C. Cottam +9 more
wiley +1 more source
The effect of glycopyrrolate vs. atropine in combination with neostigmine on cardiovascular system for reversal of residual neuromuscular blockade in the elderly: a randomized controlled trial. [PDF]
BMC AnesthesiolWang Y, Ren L, Li Y, Zhou Y, Yang J.
europepmc +1 more source
Quantitative Analysis of the Effect of Neuromuscular Blockade on Motor-Evoked Potentials in Patients Undergoing Brain Tumor Removal Surgery: A Prospective, Single-Arm, Open-Label Observational Study. [PDF]
J Clin MedChae D +8 more
europepmc +1 more source
Comparing Neuromuscular Blockade Measurement Between Upper Arm (TOF Cuff®) and Eyelid (TOF Scan®) Using Mivacurium during General Anesthesia. [PDF]
Med Sci MonitRadkowski P +3 more
europepmc +1 more source
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Neuromuscular Blockade Monitoring
Anesthesiology Clinics, 2021Neuromuscular monitoring is essential for optimal management of neuromuscular blocking drugs. Postoperative residual neuromuscular blockade continues to occur with an unacceptably high incidence and is associated with adverse patient outcomes. Use of a peripheral nerve stimulator and subjective tactile or visual assessment is useful for intraoperative ...
Wade Weigel, Stephan R. Thilen
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Acidosis and Neuromuscular Blockade
Acta Anaesthesiologica Scandinavica, 1974The effect of different types of acidosis on sensitivity to neuromuscular blocking agents was studied in vivo on the tibialis muscle of cats and in vitro in the phrenic nerve diaphragm preparation of the rat. In vivo metabolic acidification was caused by diffusion of weak organic acids, which penetrate easily into the cell and imitate closely the state
E. J. Crul-Sluijter, J. F. Crul
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