Results 361 to 370 of about 362,451 (418)
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Acidosis and Neuromuscular Blockade
Acta Anaesthesiologica Scandinavica, 1974The effect of different types of acidosis on sensitivity to neuromuscular blocking agents was studied in vivo on the tibialis muscle of cats and in vitro in the phrenic nerve diaphragm preparation of the rat. In vivo metabolic acidification was caused by diffusion of weak organic acids, which penetrate easily into the cell and imitate closely the state
E. J. Crul-Sluijter, J. F. Crul
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Reversal of Neuromuscular Blockade
International Anesthesiology Clinics, 1991Intelligent, safe use of muscle relaxants dictates that the clinician monitor neuromuscular function in all patients to determine each patient's sensitivity to relaxants. Restoration of muscle strength is a function of pharmacological antagonism of residual NMB, spontaneous recovery as the concentration of relaxant declines at the neuromuscular ...
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Cardiopulmonary implications of neuromuscular blockade
Critical Care Nursing Quarterly, 1995Neuromuscular blocking agents (NMBAs) are used to facilitate mechanical ventilation in critically ill patients. Individual NMBAs differ in their metabolism and elimination, side effects, and duration of action. These differences help designate which NMBA has the greatest efficacy, given different scenarios.
Sandmeyer, N. P., Ashworth, Lonny
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Sugammadex For Reversal of Neuromuscular Blockade: Uses and Limitations.
Current pharmaceutical design, 2019Sugammadex is a reversal agent that was engineered to reverse the effects of aminosteroid muscle relaxants. It is a modified gamma-cyclodextrin, i.e. a large glucose molecules bound in a ring like structure.
Jesse W. Hawkins +2 more
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Mastering neuromuscular blockade
Dimensions of Critical Care Nursing, 2000Learn how neuromuscular blocking agents work and how to assess and manage a patient receiving these drugs.
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Monitoring of neuromuscular blockade
Current Opinion in Anaesthesiology, 1995Neuromuscular blockade is accurately assessed by either mechanomyography or electromyography after single-twitch, train-of-four, double-burst or post-tetanic single-twitch stimuli. All of these patterns, except the single-twitch stimulus, have routine clinical use via manual evaluation of the ...
Hassan H. Ali, Richard M. Pino
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European Journal of Anaesthesiology, 2018
BACKGROUND Previous studies have reported that deep neuromuscular block (posttetanic-count 1 to 2 twitches) improves surgical conditions during laparoscopy compared with moderate block (train-of-four count: 1 to 2 twitches).
Sun-Kyung Park +5 more
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BACKGROUND Previous studies have reported that deep neuromuscular block (posttetanic-count 1 to 2 twitches) improves surgical conditions during laparoscopy compared with moderate block (train-of-four count: 1 to 2 twitches).
Sun-Kyung Park +5 more
semanticscholar +1 more source
Blockade of Neuromuscular Transmission by Zinc
Nature, 1962THE role of zinc in processes of biological interest has commanded increasing attention in recent years. Its participation as either an incidental or essentially specific component in various enzymatic reactions has been stressed by Vallee1,2. Edman has discussed in detail the action of zinc in causing relaxation of contracted glycerinated muscle ...
Alexander Sandow, Saul M. Bien
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Gentamicin and Neuromuscular Blockade
Annals of Internal Medicine, 1976Excerpt Neuromuscular blockade is a major toxicity of amino-glycoside antibiotics (1, 2). Yet gentamicin has only rarely been associated with blockade (3, 4).
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Monitoring neuromuscular blockade
Baillière's Clinical Anaesthesiology, 1994The large variability in depth and duration of neuromuscular blockade following a given dose of a neuromuscular blocking agent makes it impossible to predict its effect in an individual patient. It is obviously desirable to monitor blockade to allow drug dosage to be titrated against the individual patient's response.
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