Results 31 to 40 of about 47,410 (348)
Clindamycin-induced neuromuscular blockade [PDF]
The purpose of this article is to report the case of a patient who developed prolonged neuromuscular block after a large dose of clindamycin (2400 mg). A 58-yr-old, 65 kg woman with severe rheumatoid arthritis was admitted for wrist arthrodesis. After d-tubocurarine (3 mg) and fentanyl (1.5 micrograms.kg-1), anaesthesia was induced with thiopentone (4 ...
David R. Bevan, Osama Al Ahdal
openaire +4 more sources
Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]
Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa+6 more
core +2 more sources
Sugammadex: Breaking Through Residual Paralysis after Neostigmine’s Limits [PDF]
Persistent neuromuscular blockade following the use of Neuromuscular Blocking Agents (NMBAs) remains a significant postoperative concern, often resulting in delayed recovery and prolonged stays in the Post- Anaesthesia Care Unit (PACU).
Aparna Bagle, Sania Rodrigues
doaj +1 more source
Evaluation of the degree of neuromuscular blockade by the surgeon using clinical criteria alone is unreliable. We report a case of prolonged neuromuscular blockade lasting 5.5 h, where an additional intra-operative dose of neuromuscular relaxant was ...
James J Lamberg, Joseph F Answine
doaj +1 more source
Sugammadex, a selective antagonist of steroidal non‐depolarizing neuromuscular blocking agents, has been used in children in limited circumstances. However, neither pharmacokinetics (PKs) nor recovery profile of sugammadex for intense neuromuscular ...
Sang‐Hwan Ji+8 more
doaj +1 more source
Effects of hydrocortisone-presensitized sugammadex on recovery from neuromuscular blockade induced by rocuronium: a rodent in vivo study [PDF]
Background Sugammadex is a specific antagonist of aminosteroidal neuromuscular blocking agents with 1:1 binding to guest molecules. Sugammadex can also bind to other drugs having a steroid component in its chemical structure.
Hey-Ran Choi+5 more
doaj +1 more source
A Quantitative Neuromuscular Blockade Monitor
John P. Karis+2 more
openalex +4 more sources
Tracheal intubation without neuromuscular blocking drugs in children [PDF]
No abstract ...
Aantaa+52 more
core +1 more source
Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.+5 more
core +1 more source
A covalently bound photoisomerizable agonist. Comparison with reversibly bound agonists at electrophorus electroplaques [PDF]
After disulphide bonds are reduced with dithiothreitol, trans-3-(alpha-bromomethyl)-3’-[alpha-(trimethylammonium)methyl]azobenzene (trans-QBr) alkylates a sulfhydryl group on receptors.
Erlanger, Bernard F.+4 more
core +2 more sources