Results 31 to 40 of about 46,631 (307)

A surgeon′s assessment of inadequate neuromuscular antagonism in a case of prolonged neuromuscular blockade

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2013
Evaluation of the degree of neuromuscular blockade by the surgeon using clinical criteria alone is unreliable. We report a case of prolonged neuromuscular blockade lasting 5.5 h, where an additional intra-operative dose of neuromuscular relaxant was ...
James J Lamberg, Joseph F Answine
doaj   +1 more source

Robust fractional order PI control for cardiac output stabilisation [PDF]

open access: yes, 2019
Drug regulatory paradigms are dependent on the hemodynamic system as it serves to distribute and clear the drug in/from the body. While focusing on the objective of the drug paradigm at hand, it is important to maintain stable hemodynamic variables.
Birs, Isabela Roxana   +4 more
core   +2 more sources

Sugammadex, the Guardian of Deep Muscle Relaxation During Conventional and Robot-Assisted Laparoscopic Surgery: A Narrative Review

open access: yesDrug Design, Development and Therapy, 2021
Yan Sun,* Zhilin Wu,* Qi Wang,* Rui Chen, Shujun Sun, Yun Lin Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China*These authors ...
Sun Y   +5 more
doaj  

Residual neuromuscular blockade and late neuromuscular blockade at the post-anesthetic recovery unit: prospective cohort study

open access: yesBrazilian Journal of Anesthesiology, 2021
Introduction and objectives: The use of neuromuscular blockers during surgery represented a landmark for anesthesiology. However, their use can prompt residual Neuromuscular Blockade (RNMB) and objective monitoring of neuromuscular function is crucial to
Pedro Marcos Silva e Gonçalves   +3 more
doaj   +1 more source

Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]

open access: yes, 2013
Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
core   +3 more sources

Reversal of rocuronium‐induced intense neuromuscular blockade by sugammadex in Korean children: A pharmacokinetic and pharmacodynamic analysis

open access: yesClinical and Translational Science, 2023
Sugammadex, a selective antagonist of steroidal non‐depolarizing neuromuscular blocking agents, has been used in children in limited circumstances. However, neither pharmacokinetics (PKs) nor recovery profile of sugammadex for intense neuromuscular ...
Sang‐Hwan Ji   +8 more
doaj   +1 more source

Deep Neuromuscular Blockade During General Anesthesia: Advantages, Challenges, and Future Directions

open access: yesAnesthesia Research
Background: Neuromuscular blocking agents play an important role in modern anesthesia by facilitating optimal surgical conditions through deep muscle relaxation.
Jacob Rosenberg, Thomas Fuchs-Buder
doaj   +1 more source

Study on Neuromuscular Blockade Action of Verapamil in Albino Rats [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Background: Calcium Channel Blockers (CCBs) are now widely employed in the treatment of cardiovascular diseases and peri-operative hypertension. It has been reported that calcium channel blockers inhibit neuromuscular transmission.
JAYASHREE NAGARAL   +6 more
doaj   +1 more source

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

open access: yes, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G.   +28 more
core   +1 more source

Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]

open access: yes, 2017
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi   +99 more
core   +2 more sources

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