Results 81 to 90 of about 463 (112)
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Responses to Nondepolarizing Neuromuscular Blockers and Succinylcholine in von Recklinghausen Neurofibromatosis

Anesthesia & Analgesia, 1996
Patients with type 1 neurofibromatosis (NF-1) have been reported to have prolonged responses to nondepolarizing (ND) neuromuscular blockers (NMBs). Responses to succinylcholine (SCh) have been described as increased, decreased, or normal. The purpose of this study was to assess responses to NMBs in NF-1 patients in order to determine the clinical ...
M G, Richardson, G K, Setty, S A, Rawoof
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Reexamined: The Recommended Endotracheal Intubating Dose for Nondepolarizing Neuromuscular Blockers of Rapid Onset

Anesthesia & Analgesia, 2001
The results of any study of the relative importance of anesthetic depth versus intensity of neuromuscular block on conditions for endotracheal intubation can be manipulated by the investigator. Several independent factors, such as the depth of hypnosis induced, the interval between drug administration and laryngoscopy, the onset profile of the muscle ...
A F, Kopman, M M, Klewicka, G G, Neuman
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Steroidal Nondepolarizing Neuromuscular Blocker Induced Allergic Reactions and Role of Sugammadex in Treatment

Abant Medical Journal, 2013
Genel anestezi sırasında gelişen anafilaktik ve anafilaktoid reaksiyonların yarıdan fazlası kas gevşetici ajanlar nedeniyle oluşur. Teşhis ve uygun tedavide gecikme nedeniyle yüksek mortalite ve morbiditeyle sonuçlanan bu tür reaksiyonların önlenmesinde geleneksel destek tedavisi esastır.
TOMAK, Yakup   +2 more
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Sepsis Stage Dependently and Differentially Attenuates the Effects of Nondepolarizing Neuromuscular Blockers on the Rat Diaphragm In Vitro

Anesthesia & Analgesia, 2005
We investigated the effects of early and late sepsis on the actions of nondepolarizing neuromuscular blockers by using a rat sepsis model induced by cecal ligation and puncture. Isometric twitch tensions of nerve-hemidiaphragm preparations elicited by indirect (phrenic nerve) supramaximal stimulation at 0.1 Hz were evaluated.
Eichi, Narimatsu   +3 more
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Acute Late Sepsis Attenuates Effects of a Nondepolarizing Neuromuscular Blocker, Rocuronium, by Facilitation of Endplate Potential and Enhancement of Membrane Excitability In Vitro 

Anesthesiology, 2006
Background Sepsis attenuates the muscle-relaxing effects of nondepolarizing neuromuscular blockers. The authors investigated the effects of acute late sepsis on neuromuscular transmission and neuromuscular actions of rocuronium to clarify the mechanisms by which sepsis attenuates the effects of nondepolarizing neuromuscular ...
Tomohisa, Niiya   +2 more
openaire   +2 more sources

A Defasciculating Dose of Nondepolarizing Neuromuscular Blocker

2013
A 44-year-old obese man presented for open reduction and internal fixation of an ankle fracture. To prevent myalgia, a defasciculating dose of vecuronium was given prior to rapid-sequence induction of anesthesia with succinylcholine. The patient developed agitation and profound hypoxemia prior to direct laryngoscopy and placement of an endotracheal ...
openaire   +1 more source

Discovery of an Ultralong-acting Nondepolarizing Neuromuscular Blocker That Displays Short Onset Time and On-Demand Rapid Reversal by a Biocompatible Antagonist

Journal of Medicinal Chemistry
The combination of ultralong-acting neuromuscular block and subsequent on-demand rapid reversal may provide prolonged surgeries with improved conditions by omitting continuous or repetitive blocker administration, enabling a more stable and predictable hemodynamic profile and eliminating residual block.
Jingyu Yang   +11 more
openaire   +2 more sources

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