Results 221 to 230 of about 160,936 (251)

A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet

The FEBS Journal, EarlyView.
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr, Carmen M. Ramos, Chris D. Turner, Alexander A. Soukas, Sean P. Curran   +4 more
wiley   +1 more source

Anesthesia for thoracic surgery in infants with congenital lung malformations. [PDF]

World J Pediatr Surg
Wang R, He Y, Zhao Y, Zuo Y, Du B, Yuan M, Luo Z.   +6 more
europepmc   +1 more source

Newly identified human aminoacyl‐tRNA synthetase complex interacting multifunctional protein 2 (AIMP2) loss‐of‐function mutations cause neurodevelopmental defects linked to cell death in a zebrafish model

The FEBS Journal, EarlyView.
Human AIMP2 mutations lead to severe neurodevelopmental defects and brain atrophy. Using patient‐derived fibroblasts from two individuals, we show decreased AIMP2 protein levels and overall protein synthesis. In a zebrafish loss‐of‐function model, the lack of AIMP2 leads to an increase in cell death and results in smaller brains.
Patrick Mullen, Shenela Lakhani, Joshua Appelbaum, DéJenaé See, Pryce Patterson, Collin M. MacLeod, Alexandra George, Reza Maroofian, Margaret E. Ross, Christopher Francklyn, Alicia M. Ebert   +10 more
wiley   +1 more source

Association between beta-blocker and statin use and mental health in patients following pulmonary embolism: a prospective cohort study. [PDF]

BMC Psychol
Sabljo D, Fischer S, Berghaus TM, Linseisen J, Meisinger C, Schmitz T.   +5 more
europepmc   +1 more source

High‐resolution spatial transcriptomic atlas of mouse soleus muscle: Unveiling single cell and subcellular heterogeneity in health and denervation

The FEBS Journal, EarlyView.
Seq‐Scope maps skeletal muscle transcriptomes at high spatial resolution while preserving histological context, revealing distinct responses of myofibers, neuromuscular junctions, and stromal cells to denervation. This spatial view uncovers fiber type‐specific and localized remodeling across intact muscle tissue.
Jer‐En Hsu, Lloyd Ruiz, Yongha Hwang, Steve D. Guzman, Chun‐Seok Cho, Weiqiu Cheng, Yichen Si, Peter Macpherson, Angelo Anacleto, Qingyang Zhao, Xiaoya Zhao, Mitchell Schrank, Goo Jun, Hyun Min Kang, Myungjin Kim, Susan V. Brooks, Jun Hee Lee   +16 more
wiley   +1 more source

<i>LRP4</i>-Related Congenital Myasthenic Syndrome: Clinical, Pathophysiological, and Therapeutic Aspects. [PDF]

Muscles
Azeka FYK, Serrano PL, Seneor DD, Calegaretti SL, Pinheiro MM, Martins MV, Guilherme LM, Barile JP, Mendes PM, Garcia LHMR, Galvão MJTC, Gama SM, Cavalheiro RBR, Farias IB, Machado RIL, Pinto WBVR, Oliveira ASB, Sgobbi P.   +17 more
europepmc   +1 more source

Suzetrigine: A promising analgesic targeting voltage-gated sodium channel. [PDF]

Indian J Pharmacol
Dey S, Eeshwar MV, Chamala V, Gupta SK.
europepmc   +1 more source

Pragmatic Phenotype-Electrophysiology-Genomics Integration in Pediatric Congenital Myasthenic Syndromes: Insights From 36 Patients in a Single-Center Study in China. [PDF]

CNS Neurosci Ther
Cui L, Ma K, Fu X, Ge L, Jia B, Ma W, Yang L, Liu Z, Lv J, Xu W, Wang L, Zhao G, Li J, Wu J, Wang Q, Ding C, Ren X, Shen X, Xiong H.   +18 more
europepmc   +1 more source