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Disadvantages of Neuromuscular Blocking Agents
Veterinary Clinics of North America: Small Animal Practice, 1992Neuromuscular blocking agents have few indications and significant contraindications or problems associated with their use. The need for controlled ventilation and the difficulties of monitoring anesthetic depth when using neuromuscular blocking agents are overriding factors that mitigate against their routine use.
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Interactions of serotonin with neuromuscular blocking agents
European Journal of Pharmacology, 1972Abstract Serotonin has been shown to reverse blockade induced by the nondepolarizing agents and hemicholinium and to potentiate blockade produced by the depolarizers. It is more effective at low frequencies of stimulation. The drug augments the twitch potentiations produced by small doses of decamethonium and neostigmine.
K.L. Dretchen +2 more
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Neuromuscular blocking agents and reversal agents
Anaesthesia & Intensive Care Medicine, 2005Abstract The neuromuscular blocking agents in routine clinical use may be classed as depolarizing or nondepolarizing. Suxamethonium is the only example of the depolarizing group and is an agonist at the neuromuscular receptor. It has the most rapid onset and the shortest duration of action, though it has a number of important unwanted side-effects ...
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Neuromuscular Blocking Agents and Neuromuscular Diseases
2000Acquired neuromuscular diseases or congenital disorders either affect the neuromuscular transmission or the muscle itself. When the neuromuscular transmission is involved, two pathophysiological mechanisms must be distinguished: the abnormality of the nicotinic receptor at the endplate (myasthenia gravis, upregulation of the receptor) and the ...
Benoit Plaud, François Donati
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