Results 31 to 40 of about 1,681,336 (179)

Neuromuscular blockers and their reversal: have we finally found the on-off switches?

open access: yesAin Shams Journal of Anesthesiology, 2021
Background A nondepolarizing neuromuscular blocking agent (NMBA) with a succinylcholine-like quick onset and offset has been the holy grail of the science of neuromuscular blockade.
Shagun Bhatia Shah   +3 more
doaj   +1 more source

Pancuronium Bromide for Chemical Immobilization of Adult Nile Crocodiles (Crocodylus niloticus): A Field Study

open access: yesAnimals, 2023
(1) Background: Pancuronium bromide is a neuromuscular blocker used for immobilizing crocodiles that can be reversed with neostigmine. A recommended drug dose has only been established for saltwater crocodiles (Crocodylus porosus), mostly based on trials
Lionel Schilliger   +6 more
doaj   +1 more source

Reversal of rocuronium‐induced intense neuromuscular blockade by sugammadex in Korean children: A pharmacokinetic and pharmacodynamic analysis

open access: yesClinical and Translational Science, 2023
Sugammadex, a selective antagonist of steroidal non‐depolarizing neuromuscular blocking agents, has been used in children in limited circumstances. However, neither pharmacokinetics (PKs) nor recovery profile of sugammadex for intense neuromuscular ...
Sang‐Hwan Ji   +8 more
doaj   +1 more source

Farmacocinética y farmacodinamia del bromuro de rocuronio: Influencia de la terapia crónica con fenitoína. [PDF]

open access: yes, 2010
[spa] ANTECEDENTES: La administración crónica de fármacos antiepilépticos disminuye la intensidad del efecto de los fármacos bloqueantes neuromusculares (BNM), aunque existe cierta discrepancia a la hora de explicar si esta interacción se produce a nivel
Fernández Candil, Juan Luís
core   +6 more sources

Muscle relaxants in paediatric day case surgery

open access: yes, 2001
It has been estimated that more than 60% of all paediatric surgery is performed on a day case basis. The benefits of this type of surgery in children include reduced costs, avoidance of the stress of hospitalization and less disruption to family life ...
Meakin, G. H.
core   +8 more sources

Preparing for the unexpected: special considerations and complications after sugammadex administration

open access: yesBMC Anesthesiology, 2017
Sugammadex, a modified gamma-cyclodextrin, has changed clinical practice of neuromuscular reversal dramatically. With the introduction of this selective relaxant binding agent, rapid and reliable neuromuscular reversal from any depth of block became ...
Hajime Iwasaki   +3 more
doaj   +1 more source

INFLUENCE OF “PRIMING” ON THE POTENCY OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS

open access: yesBritish Journal of Anaesthesia, 1987
Dose-response curves have been constructed to determine the ED50 and ED95 (doses required to produce a 50% and a 95% block, respectively) following administration of a small "priming" dose of atracurium 50 micrograms kg-1, vecuronium 10 micrograms kg-1 or pancuronium 10 micrograms kg-1.
M M, Brady, R K, Mirakhur, F M, Gibson
openaire   +2 more sources

Function and distribution of three types of rectifying channel in rat spinal root myelinated axons [PDF]

open access: yes, 1987
1. The nature, distribution and function of rectifying channels in rat spinal root myelinated axons has been assessed with selective blocking agents and a variety of intracellular and extracellular recording techniques. 2.
Baker, M.   +3 more
core   +2 more sources

Are non-depolarizing neuromuscular blocking agents innocuous for the neonates? [PDF]

open access: yesCanadian Journal of Anesthesia/Journal canadien d'anesthésie, 2005
tions and for the initial injection when a continuous infusion is used (for continuous plexus nerve block analgesia). Unfortunately, the labelled syringe used for continuous infusion is not a dedicated one (30 mL is too small: too frequent changes are needed). We use dedicated coiled lines as well (Figure, Vygon laboratories, Ecouen, France).
openaire   +1 more source

Conventional reversal of rocuronium-induced neuromuscular blockade by sugammadex in Korean children: pharmacokinetics, efficacy, and safety analyses

open access: yesFrontiers in Pharmacology, 2023
Background: Sugammadex is known to reverse neuromuscular blockade induced by non-depolarizing agents. In children, the recommended dose for reversal of moderate neuromuscular blockade is 2 mg/kg.
Sang-Hwan Ji   +17 more
doaj   +1 more source

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