Results 151 to 160 of about 1,681,336 (179)

Cardiac effects of non-depolarizing neuromuscular blocking agents pancuronium, vecuronium, and rocuronium in isolated rat atria

General Pharmacology: The Vascular System, 1999
Pancuronium, vecuronium, and rocuronium produce different cardiac effects. Using spontaneously beating right and electrically stimulated left rat atria, while measuring developed force, effective refractory period, and heart rate, we determined and compared the concentration-dependent cardiac effects of the compounds.
A L, Melnikov, K Y, Malakhov, K G, Helgesen, D A, Lathrop   +3 more
openaire   +2 more sources

An analytical pharmacodynamic model for nondepolarizing neuromuscular blocking agents

Journal of Pharmacokinetics and Biopharmaceutics, 1981
A pharmacodynamic model for nondepolarizing neuromuscular blocking agents (NMBA) is developed and tested with different sets of data (NMBA plasma concentration and time evolution of muscular paralysis). This model takes into account the binding of NMBA to the cholinergic motor endplate receptors and thus permits estimation of the apparent equilibrium ...
D'Hollander, Alain, Delcroix, Claude
openaire   +5 more sources

Pharmacokinetics of pipecurium bromide, a new non-depolarizing neuromuscular blocking agent, in humans.

Arzneimittel-Forschung, 1982
The pharmacokinetics of 2 beta, 16 beta-bis-(4'-dimethyl-1'-piperazino)-3 alpha, 17 beta-diacetoxy-5 alpha-androstane dibromide (pipecurium bromide, Arduan), a new non-depolarizing neuromuscular blocking agent, was studied in surgical patients. Plasma concentration-time curves of pipecurium bromide were evaluated by fitting the data to a bi-exponential
E, Tassonyi, G, Szabó, L, Vereczkey
openaire   +1 more source

Comparison of neuromuscular action of rocuronium, a new steroidal non-depolarizing agent, with vecuronium.

Acta anaesthesiologica Sinica, 1998
Rocuronium is a new nondepolarizing muscle relaxant. It features a rapid onset and lack of histamine release: It has an intermediate onset of action as vecuronium. The purpose of this study was to compare the neuromuscular action and condition of intubation after a bolus dose of rocuronium or vecuronium (2 x ED90).
P L, Lin, C C, Liu, S Z, Fan, A, Chao, S C, Shin, Y T, Tai   +5 more
openaire   +1 more source

DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS AND INTRAOCULAR PRESSURE IN VIVO

Anesthesiology, 1957
J B, DILLON, P, SABAWALA, D B, TAYLOR, R, GUNTER   +3 more
openaire   +2 more sources

Determination of pipecurium bromide, a new non-depolarizing neuromuscular blocking agent, in human serum.

Arzneimittel-Forschung, 1981
A method for the determination of 2 beta, 16 beta-bis (4'dimethyl-1'-piperazino)-3a, 17 beta-diacetoxy-5 alpha-androstane is described. After deproteinization a pipecurium bromide Rose Bengal complex is formed and extracted with chloroform from a mildly basic medium.
G, Szabó, E, Tassonyi
openaire   +1 more source

THE MECHANISMS UNDERLYING NEUROMUSCULAR BLOCK FOLLOWING PROLONGED EXPOSURE TO DEPOLARIZING AGENTS*

Annals of the New York Academy of Sciences, 1966
A J, Gissen, W L, Nastuk
openaire   +2 more sources

A Modified Train-of-Four Ratio to Assess Recovery From Depolarizing Neuromuscular Blockade After Succinylcholine, a Prospective Observational Study

Journal of Clinical Monitoring and Computing, 2021
Denis Schmartz, Cédric Baumann
exaly  

Neuromuscular Blocking Agents and Reversal Agents

Anaesthesia and Intensive Care Medicine, 2021
Jennifer M Hunter
exaly  

The depolarizing and non-depolarizing neuromuscular blocking agents.

Wisconsin medical journal, 1974
S, Lamid, R I, Wang
openaire   +1 more source