Results 41 to 50 of about 3,372 (158)

Anaesthetic management in a patient with multiple sclerosis

Indian Journal of Anaesthesia, 2011
Multiple sclerosis (MS) is a rare autoimmune demyelinating disorder of the central nervous system clinically manifesting as periodic attacks of varied neurologic symptoms, eventually progressing to fixed neurologic deficits and disability.
Lata M Kulkarni, C S Sanikop, H L Shilpa, Anupama Vinayan   +3 more
doaj   +1 more source

Extreme Paralysis Following Rocuronium Administration in a Myasthenia Gravis Patient: A Case Report

Clinical Practice and Cases in Emergency Medicine, 2023
Introduction: The use of paralytics during rapid sequence intubation (RSI) in patients with myasthenia gravis (MG) remains a controversial topic in emergency medicine.
Kelsey Billups, Charlotte Collins, Aimee Weber   +2 more
doaj   +1 more source

EFFECTS OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS ON PERIPHERAL AUTONOMIC MECHANISMS IN CATS

British Journal of Anaesthesia, 1976
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with effects on autonomic mechanisms in anaesthetized cats. Whereas autonomic blockade with tubocurarine occurred at parasympathetic and sympathetic ganglia, neuromuscular paralysing doses of gallamine, alcuronium, pancuronium and fazadinium caused blockade at vagal ...
R, Hughes, D J, Chapple
openaire   +2 more sources

Optimizing Organ Donation After Euthanasia: A Critical Appraisal

Transplantology
This Critical Appraisal aims to explore the pharmacokinetics and pharmacodynamics of medications used in organ donors after euthanasia (ODE) and their impact on abdominal organ quality.
E. A. J. Alkemade, H. D. Lam, B. J. C. Hendriks, A. E. Braat, I. P. J. Alwayn, M. J. Coenraad, A. G. Baranski   +6 more
doaj   +1 more source

Biomimetic 3D Tactile Sensor System With Neuromorphic Encoding for Fascicle‐Level Feedback

Advanced Intelligent Systems, EarlyView.
A 3D biomimetic tactile sensor system converts skin‐like mechanical interactions into neural stimulation‐ready spike patterns. Embedded slow‐ and fast‐adapting sensors distinguish sustained pressure from transient touch, while neuromorphic encoding preserves their temporal signatures.
Minseok Kim, Jaeu Park, Minseok Kang, Yongwoo Kim, Sanghoon Lee   +4 more
wiley   +1 more source

Supramolecular therapeutics to treat the side effects induced by a depolarizing neuromuscular blocking agent

Theranostics, 2019
Succinylcholine (Sch) is the only depolarizing neuromuscular blocking agent widely used for rapid sequence induction in emergency rooms. Unfortunately, a variety of (sometimes lethal) adverse effects, such as hyperkalemia and cardiac arrest, are associated with its use, and currently there are no specific antidotes to reverse Sch or to treat these side-
Zhang, Xiangjun, Cheng, Qian, Li, Lanlan, Shangguan, Liqing, Li, Chenwen, Li, Shengke, Huang, Feihe, Zhang, Jianxiang, Wang, Ruibing   +8 more
openaire   +2 more sources

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Effects of Neostigmine and Sugammadex for Reversal of Neuromuscular Blockade on QT Dispersion Under Propofol Anesthesia: A Randomized Controlled Trial

Cardiology and Therapy, 2018
Introduction Reversal of non-depolarizing neuromuscular blocking agent neostigmine is associated with QT prolongation under general anesthesia. To clarify the effects of neostigmine and sugammadex on hemodynamic status, the QT interval and QT dispersion ...
Yusuke Yamashita, Toshifumi Takasusuki, Yoshiyuki Kimura, Makoto Komatsuzaki, Shigeki Yamaguchi   +4 more
doaj   +1 more source

EFFECTS OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS ON THE CARDIAC VAGUS NERVE IN THE GUINEAPIG

British Journal of Anaesthesia, 1980
The ability of gallamine, metocurine, pancuronium, tubocurarine and atropine to block the response to postganglionic stimulation of the vagus nerve were measured in isolated, spontaneously beating guineapig atria. From analysis of the results in conjunction with those of earlier assays of concentrations that block effects of preganglionic vagal ...
S L, Son, D R, Waud
openaire   +2 more sources

Perioperative Adverse Events in Primary Palatoplasty: “Risk Factors and Impact on Care Escalation in a Multicenter Cohort”

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Patients undergoing palatoplasty experience perioperative adverse events. Identifying risk factors for perioperative adverse events and escalation of care may improve outcomes. Methods Pediatric patients undergoing primary palatoplasty were included in this retrospective observational study performed at two academic children's ...
Febina Padiyath, Elizabeth M. O'Brien, Jennifer Nam, Paula Hu, Nishil Mehta, Marc Parris, Anthony Alexander, Ashley Hodges, Goretti Chiang, Vinícius Caldeira Quintão, Ricardo Vieira Carlos, Gabriel Soares de Sousa, Asif Padiyath, Susan C. Nicolson, John Fiadjoe, Oksana A. Jackson, Lisa K. Lee, Annery G. Garcia‐Marcinkiewicz   +17 more
wiley   +1 more source