Results 161 to 170 of about 1,286,377 (194)

Clinical pharmacology of ORG 7617, a short-acting non-depolarizing neuromuscular blocking agent

European Journal of Clinical Pharmacology, 1994
The dose-response relationship and the time course of action of Org 7617, a short acting non-depolarizing neuromuscular blocking agent, were evaluated during thiopentone, fentanyl, halothane and N2O anaesthesia. Neuromuscular transmission was monitored mechanomyographically. The ED50 and ED90 were calculated after single bolus doses of the drug. Twelve,
van den Broek, L, Wierda, JMKH, PROOST, JH, Hommes, FDM, Agoston, S   +4 more
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Interactions between ORG9426 and other non-depolarizing neuromuscular blocking agents in ratsin vivo

Journal of Anesthesia, 1992
In this study, combined neuromuscular blocking effects of ORG9426 with other non-depolarizing neuromuscular blocking agents were investigated. About 20% steady state neuromuscular block was established by a continuous infusion of one of 6 neuromuscular blocking agents (ORG9426, vecuronium, pancuronium, pipecuronium, d-tubocurarine and metocurine). Then
Kazuhiko Watanabe
exaly   +3 more sources

Increased Sensitivity to Depolarizing and Nondepolarizing Neuromuscular Blocking Agents in Young Rat Hemidiaphragms

Anesthesiology, 2001
Background Newborn neuromuscular junctions are more sensitive to d-tubocurarine than more mature preparations. It is unclear whether the same modifications occur with newer nondepolarizing agents and depolarizing agent succinylcholine.
Richard Robitaille, F Donati, Donati François   +2 more
exaly   +3 more sources

Interactions of Volatile Anesthetics with Non-Depolarizing Neuromuscular Blocking Agents

1995
Drug interactions involving neuromuscular blocking agents are divided into two classes: one is interaction between neuromuscular blocking drugs and other classes of drug.The second is interactions with neuromuscular blocking agents each other.
Fukushima Kazuaki
exaly   +2 more sources

DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS AND INTRAOCULAR PRESSURE IN VIVO

Anesthesiology, 1957
J B Dillon, D B Taylor, Dillon John B
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THE MECHANISMS UNDERLYING NEUROMUSCULAR BLOCK FOLLOWING PROLONGED EXPOSURE TO DEPOLARIZING AGENTS

Annals of the New York Academy of Sciences, 1966
A J, Gissen, W L, Nastuk
exaly   +3 more sources

A modified train-of-four ratio to assess recovery from depolarizing neuromuscular blockade after succinylcholine, a prospective observational study

Journal of Clinical Monitoring and Computing, 2020
Succinylcholine is still used in clinical practice. Its duration is highly variable and neuromuscular monitoring is recommended to assess its recovery. Unfortunately, depolarizing neuromuscular block cannot be evaluated by train-of-four (TOF) as no fade ...
Denis Schmartz, Fuchs-Buder Thomas
exaly   +2 more sources

Two new short-acting non-depolarizing neuromuscular blocking agents

Experientia, 1972
Le chlorure de 1,1′-octamethylene et le methylsulfate de 5,5′-octamethylenebis ont chez le chat un effet de blocage neuro-musculaire non depolarisant, de courte duree. Les comparaisons faites avec des analogues voisins suggerent que l'activite de ces composes est influencee par le degre d'empechement sterique autour des atomes d'azote quaternaire.
F C, Copp, G G, Coker, A F, Green, R, Hughes, R H, Nimmo-Smith   +4 more
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A study in vitro of new short-acting, non-depolarizing neuromuscular blocking agents

Biochemical Pharmacology, 1969
Abstract Presently available short-acting, depolarizing myoneural blocking agents have significant side effects such as increased intraocular tension, cardiac arrhythmias desensitization of the postjunctional membrane, skeletal muscle injury and muscle pains. Non-depolarizing blocking drugs do not produce profound blocks of short duration.
R J, Kitz, J H, Karis, S, Ginsburg
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Effect of Lignocaine on the Responses Produced by Depolarizing Agents at the Chick Neuromuscular Junction

Acta Anaesthesiologica Scandinavica, 1984
The effect of lignocaine on the depolarization and contracture responses produced by acetylcholine (ACh) or tetraethylammonium (TEA) was studied in the isolated chick biventer cervicis (BVC) nerve‐muscle preparation using the moving fluid electrode technique.
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