Results 71 to 80 of about 3,526 (188)

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan   +3 more
wiley   +1 more source

Patient safety: reversal of neuromuscular blocking agents

open access: yes, 2014
NORSK: Restcurarisering er en fryktet komplikasjon etter generell anestesi der pasienter har fått ikke-depolariserende nevromuskulær blokade (NMB).
Martinsen, Hege   +1 more
core   +1 more source

Use of Sugammadex after Neostigmine Incomplete Reversal of Rocuronium-Induced Neuromuscular Blockade

open access: yes, 2012
SummaryBackground and objectivesNeuromuscular blockers (NMB) have been used for more than half of a century in anesthesia and have always been a challenge for anesthesiologists.
Peceguini, Lilian Akemi Moore   +8 more
core   +1 more source

Effect of anaesthetic and choice of neuromuscular blocker on vagal control of heart rate under laboratory animal experimental conditions

open access: yes, 2017
Neuromuscular-blocking agents are commonly used in laboratory animal research settings. Due to actions of cholinergic receptors at locations other than the motor end-plate, these agents have a strong propensity to modulate autonomic outflow and may ...
Mark Tahmindjis   +3 more
core   +1 more source

Analytical model of some pharmacokinetic and pharmacodynamic properties of fazadinium in man

open access: yes, 1983
The neuromuscular blocking characteristics and plasma concentration decay of fazadinium bromide, a short acting, non-depolarizing muscular relaxant, were simultaneously observed under standardised conditions in 6 healthy, anaesthetized, adult patients ...
Duvaldestin, Philippe   +5 more
core   +1 more source

Aktuelni problemi u primeni mišićnih relaksanata u kliničkoj praksi [PDF]

open access: yesVojnosanitetski Pregled, 2003
Konstantinović Slavko, Balkanov Trajan
doaj   +1 more source

Comparative Study of Efficacy and Safety of Rocuronium Bromide with Suxamethonium Chloride for Tracheal Intubation

open access: yesNational Journal of Medical Research
Background: Tracheal intubation is a cornerstone of modern anesthetic practice, with neuromuscular blocking agents playing a critical role. Among these agents, Suxamethonium chloride is widely used for its quick onset and brief duration.
Asawari Wagh   +3 more
doaj   +1 more source

Studies on Neuromuscular Blocking Agents and Their Antagonists During Anaesthesia [PDF]

open access: yes, 2011
Neuromuscular blocking agents (NMBAs) are widely used in clinical anaesthesia and emergency medicine. Main objectives are to facilitate endotracheal intubation and to allow surgery by reducing muscle tone and eliminating sudden movements, which may ...
Illman, Hanna
core  

Pharmacological interventions for the management of anesthesia and sedation in patients with Duchenne muscular dystrophy: a systematic review and meta-analysis

open access: yesFrontiers in Medicine
BackgroundPatients with duchenne muscular dystrophy (DMD) have an increased risk of complications when they undergo sedation or general anesthesia. However, due to improvements in cardiopulmonary therapies during anesthetic care, patients with DMD are ...
Xianghong Lian   +14 more
doaj   +1 more source

EVALUATION OF GLYCOPYRROLATE AND ATROPINE AS ADJUNCTS TO REVERSAL OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS IN A “TRUE-TO-LIFE” SITUATION

open access: yesBritish Journal of Anaesthesia, 1980
Glycopyrrolate, a quaternary ammonium anticholinergic compound, and atropine were evaluated in combination with neostigmine for antagonism of non-depolarizing neuromuscular block. A total of 641 patients were investigated in a "true-to-life" situation.
D A, Cozanitis   +4 more
openaire   +2 more sources

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