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Perioperative Considerations in a Patient With Oculopharyngeal Muscular Dystrophy: A Case Report. [PDF]
CureusBajaj P, Overholt D, Chura M.
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Neuromuscular Blocking Agents and Reversal Agents
Anaesthesia and Intensive Care Medicine, 2005 The neuromuscular blocking agents in routine clinical use may be classed as depolarizing or nondepolarizing. Suxamethonium is the only example of the depolarizing group and is an agonist at the neuromuscular receptor.
Brian J Pollard
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Depolarizing Neuromuscular Blocking Agents
2017Succinylcholine was first introduced into clinical practice in the 1950s, and is currently the only depolarizing neuromuscular blocker in use. It is unique among the drugs used for muscle relaxation in its rapid onset and short duration of action. These characteristics account for its extensive use in scenarios requiring emergency control of the airway.
Caroline S. Gross, Zhiling Xiong
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Two new short-acting non-depolarizing neuromuscular blocking agents
Experientia, 1972Le chlorure de 1,1′-octamethylene et le methylsulfate de 5,5′-octamethylenebis ont chez le chat un effet de blocage neuro-musculaire non depolarisant, de courte duree. Les comparaisons faites avec des analogues voisins suggerent que l'activite de ces composes est influencee par le degre d'empechement sterique autour des atomes d'azote quaternaire.
F C, Copp +4 more
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Anesthesiology, 2001
Background Newborn neuromuscular junctions are more sensitive to d-tubocurarine than more mature preparations. It is unclear whether the same modifications occur with newer nondepolarizing agents and depolarizing agent succinylcholine.
L P, Fortier, R, Robitaille, F, Donati
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Background Newborn neuromuscular junctions are more sensitive to d-tubocurarine than more mature preparations. It is unclear whether the same modifications occur with newer nondepolarizing agents and depolarizing agent succinylcholine.
L P, Fortier, R, Robitaille, F, Donati
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A study in vitro of new short-acting, non-depolarizing neuromuscular blocking agents
Biochemical Pharmacology, 1969Abstract Presently available short-acting, depolarizing myoneural blocking agents have significant side effects such as increased intraocular tension, cardiac arrhythmias desensitization of the postjunctional membrane, skeletal muscle injury and muscle pains. Non-depolarizing blocking drugs do not produce profound blocks of short duration.
R J, Kitz, J H, Karis, S, Ginsburg
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Acta Anaesthesiologica Scandinavica, 1984
The effect of lignocaine on the depolarization and contracture responses produced by acetylcholine (ACh) or tetraethylammonium (TEA) was studied in the isolated chick biventer cervicis (BVC) nerve‐muscle preparation using the moving fluid electrode technique.
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The effect of lignocaine on the depolarization and contracture responses produced by acetylcholine (ACh) or tetraethylammonium (TEA) was studied in the isolated chick biventer cervicis (BVC) nerve‐muscle preparation using the moving fluid electrode technique.
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Acta Anaesthesiologica Scandinavica, 1980
We describe the clinical use, for intubation purposes, of Org‐NC45, a new non‐depolarizing neuromuscular blocking agent. Administration of 50 and 72 μg/kg of this drug allowed good to excellent endotracheal intubation conditions within 3 and 2 min, respectively. In none of the cases was a signifcant change in blood pressure or heart rate seen after the
N, Krieg +3 more
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We describe the clinical use, for intubation purposes, of Org‐NC45, a new non‐depolarizing neuromuscular blocking agent. Administration of 50 and 72 μg/kg of this drug allowed good to excellent endotracheal intubation conditions within 3 and 2 min, respectively. In none of the cases was a signifcant change in blood pressure or heart rate seen after the
N, Krieg +3 more
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Combining non-depolarizing neuromuscular blocking agents: synergism, addition or antagonism?
Current Opinion in Anaesthesiology, 1999As the quality of currently available relaxants has improved, the need to combine relaxants to minimize the incidence and severity of their side-effects has decreased. Little work has been done in the past year characterizing the effects of combining different non-depolarizing neuromuscular blocking agents.
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Interactions of Volatile Anesthetics with Non-Depolarizing Neuromuscular Blocking Agents
1995Drug interactions involving neuromuscular blocking agents are divided into two classes: one is interaction between neuromuscular blocking drugs and other classes of drug.The second is interactions with neuromuscular blocking agents each other.
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