Results 141 to 150 of about 10,730,025 (313)

Magnetic Resonance Imaging Modified Dixon Fat Quantification Analysis Is a Quantitative and Reliable Method for Evaluating Fatty Atrophy of the Hamstring Muscle Complex After Proximal Avulsion Injury

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the reliability and validity of objective fat quantification using the modified Dixon magnetic resonance imaging sequence for assessing fatty degeneration in conservatively treated patients with proximal hamstring avulsion injuries. Methods Magnetic resonance imaging with modified Dixon sequence was used.
John Hanke, Philipp Schenk, Irga Kemal, Markus Heinecke, Philipp Kobbe, Thomas Mendel   +5 more
wiley   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Transtibial Anterior Cruciate Ligament Reconstruction Using a Synthetic Graft Combined With Remnant Repair: A Hybrid Technique

Arthroscopy Techniques, EarlyView.
Abstract The purpose of this technical note is to describe a hybrid arthroscopic technique that combines anterior cruciate ligament reconstruction using a synthetic graft with concomitant remnant repair. Following diagnostic arthroscopy and assessment of remnant quality, tibial and femoral tunnels are created using a transtibial approach with attention
Peng Wang, Yirui Han, Weibo Yin, Yufei Zhang, Weiliang Zhong   +4 more
wiley   +1 more source

The Prevalence of Sleep-Disordered Breathing in Children With Neuromuscular Diseases. [PDF]

Cureus
Al-Naimi AR, Toma HM, Ibrahim K, Abushahin M, Abushahin A.   +4 more
europepmc   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Oscillometry is more feasible than spirometry in children with neuromuscular diseases. [PDF]

ERJ Open Res
Smolkova M, Rose M, Polychronakis T.
europepmc   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Patient Preferences in Neuromuscular Diseases: Insights for Future Drug Development. [PDF]

JIMD Rep
Jimenez-Moreno AC, Blain A, Pinto CA, Soekhai V, Johansson JV, Dyer C, Adcock K, de Bekker-Grob EW, de Wit GA, Newman J, Gorman GS.   +10 more
europepmc   +1 more source

Neuromuscular diseases: Diagnosis and management.

Orthopaedics & Traumatology: Surgery & Research, 2017
P. Mary, Laurent Servais, Raphaël Vialle   +2 more
semanticscholar   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source