Results 161 to 170 of about 2,421,984 (303)

Construct Validity and Reliability of the OMNI Scale in Children and Adolescents With Neuromuscular Diseases. [PDF]

Muscle Nerve
Cardoso J, Tonoli CC, Buzzetti BP, Davoli GB, Mattiello-Sverzut AC.   +4 more
europepmc   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Correction: Establishing polysomnographic criteria for initiation of non-invasive ventilation in children with neuromuscular diseases. [PDF]

J Clin Sleep Med
Dannenberg VC, Amin R, Anagnostopoulos G, Adeleye A, Bendiak GN, Kolski H, Castro-Codesal ML.   +6 more
europepmc   +1 more source

From muscle fibres to muscle gears: how dynamic fascicle orientation and shape change impact skeletal muscle function

Biological Reviews, EarlyView.
ABSTRACT Skeletal muscle architectural design strongly affects force‐generating capacity and excursion range, and its functional importance to animal and human movement is well founded. Traditionally, this ‘structure–function relation’ has been inferred from architecture measurements with muscles at rest (from anatomical dissections or medical imaging ...
Matheus D. Pinto, James M. Wakeling, Javier A. Almonacid, Anthony J. Blazevich   +3 more
wiley   +1 more source

From Variant Interpretation to Biomarker Translation: Multi-omics Integration in Inherited Neuromuscular Diseases. [PDF]

Hum Mutat
Zhang S, Lang X, Liu L.
europepmc   +1 more source

Profession‐Related Accreditation Requirements in Australia Regarding Anatomy Teaching: A Web‐Based Desktop Audit

Clinical Anatomy, EarlyView.
ABSTRACT For effective and safe practice, health professionals need an understanding of functional anatomy. Registration boards, councils or self‐regulating professional associations determine the standards, codes, graduate competencies and education program accreditation requirements which inform health curricula development and content.
Anita Zacharias, Daniel J. English, Jennifer Selkirk‐Bell, Kelly Fielden, Bradley Halliday, Carol McKinstry   +5 more
wiley   +1 more source

The Prevalence of Sleep-Disordered Breathing in Children With Neuromuscular Diseases. [PDF]

Cureus
Al-Naimi AR, Toma HM, Ibrahim K, Abushahin M, Abushahin A.   +4 more
europepmc   +1 more source

Novel Applied Bayesian Statistics for Monitoring Neuromuscular Diseases

Novel Applied Bayesian Statistics for Monitoring Neuromuscular Diseases. Neurological diseases such as motor neurone disease are caused by the progressive death of motor units serving a muscle.

core