Results 61 to 70 of about 2,312,065 (203)

Resistance Exercise Training in McArdle Disease: Myth or Reality?

Case Reports in Neurological Medicine, 2018
McArdle disease is a metabolic myopathy mainly characterised by symptom onset during physical activities or isometric muscle contraction. Resistance (also termed strength) training is a type of physical exercise focusing on the use of resistance (e.g ...
Aleksandra Pietrusz, Renata S. Scalco, Ros Quinlivan   +2 more
doaj   +1 more source

A multicenter cross-sectional French study of the impact of COVID-19 on neuromuscular diseases

Orphanet Journal of Rare Diseases, 2021
Background Due to their health condition, patients with neuromuscular diseases (NMD) are at greater risk of developing serious complications with COVID-19.
Lucie Isoline Pisella, Sara Fernandes, Guilhem Solé, Tanya Stojkovic, Céline Tard, Jean-Baptiste Chanson, Françoise Bouhour, Emmanuelle Salort-Campana, Guillemette Beaudonnet, Louise Debergé, Fanny Duval, Aude-Marie Grapperon, Marion Masingue, Aleksandra Nadaj-Pakleza, Yann Péréon, Frédérique Audic, Anthony Behin, Diane Friedman, Armelle Magot, Jean-Baptiste Noury, Sarah Souvannanorath, Karim Wahbi, Jean-Christophe Antoine, Kévin Bigaut, Jean-Philippe Camdessanché, Pascal Cintas, Rabab Debs, Caroline Espil-Taris, Laurent Kremer, Thierry Kuntzer, Pascal Laforêt, Vincent Laugel, Martial Mallaret, Maud Michaud, Sylvain Nollet, Juliette Svahn, Savine Vicart, Rocio Nur Villar-Quiles, Isabelle Desguerre, David Adams, Sandrine Segovia-Kueny, Géraldine Merret, Elhadi Hammouda, Annamaria Molon, Shahram Attarian   +44 more
doaj   +1 more source

Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice

Disease Models & Mechanisms, 2020
Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's Disease, is a late-onset X-linked progressive neuromuscular disease, which predominantly affects males.
Anna L. Gray, Leonette Annan, James R. T. Dick, Albert R. La Spada, Michael G. Hanna, Linda Greensmith, Bilal Malik   +6 more
doaj   +1 more source

Real-world multidisciplinary outcomes of onasemnogene abeparvovec monotherapy in patients with spinal muscular atrophy type 1: experience of the French cohort in the first three years of treatment

Orphanet Journal of Rare Diseases
Background Spinal muscular atrophy type 1 (SMA1) is the most severe and early form of SMA, a genetic disease with motor neuron degeneration. Onasemnogene abeparvovec gene transfer therapy (GT) has changed the natural history of SMA1, but real-world data ...
Isabelle Desguerre, Rémi Barrois, Frédérique Audic, Christine Barnerias, Brigitte Chabrol, Jean Baptiste Davion, Julien Durigneux, Caroline Espil-Taris, Marta Gomez-Garcia de la Banda, Marine Guichard, Arnaud Isapof, Marie Christine Nougues, Vincent Laugel, Laure Le Goff, Sandra Mercier, Anne Pervillé, Christian Richelme, Marie Thibaud, Catherine Sarret, Cyril Schweitzer, Hervé Testard, Valérie Trommsdorff, Catherine Vanhulle, Ulrike Walther-Louvier, Cécilia Altuzarra, Mondher Chouchane, Juliette Ropars, Susana Quijano-Roy, Claude Cances   +28 more
doaj   +1 more source

Advances in Treatment of ATTRv Amyloidosis: State of the Art and Future Prospects

Brain Sciences, 2020
Hereditary amyloid transthyretin (ATTRv) amyloidosis with polyneuropathy is a progressive disease that is transmitted as an autosomal dominant trait and characterized by multiple organ failure, including axonal sensory-motor neuropathy, cardiac ...
Massimo Russo, Luca Gentile, Antonio Toscano, M’Hammed Aguennouz, Giuseppe Vita, Anna Mazzeo   +5 more
doaj   +1 more source

Neuromuscular fatigability during repeated-sprint exercise in male athletes [PDF]

, 2015
Purpose - To determine the pattern of neuromuscular fatigability that manifests during repeated sprint running exercise. Methods - Twelve male participants (mean ± SD age, 25 ± 6 yr; stature, 180 ± 7 cm; body mass, 77 ± 7 kg), currently training and ...
Thomas, Kevin, Goodall, Stuart, Howatson, Glyn, Charlton, Kayleigh   +3 more
core   +1 more source

NEUROMUSCULAR DISEASE AND ANAESTHESIA

British Journal of Anaesthesia, 1974
Diseases affecting the neuromuscular system are numerous and not uncommon (for classification see Appendix). Almost all of the drugs used in anaesthesia have either a direct or an indirect effect on muscle, and so an understanding by anaesthetists of the neuromuscular diseases is essential in view of the universal requirement of muscle relaxation ...
openaire   +2 more sources

Neuromuscular diseases [PDF]

Neuromuscular diseases (NMD) are a heterogeneous group of disorders that affect the peripheral nervous system and muscles, with symptoms such as weakness, numbness, tingling, and muscle cramps. Weakness can affect many muscles.
Ozyilmaz, Ayşegül
core   +2 more sources

Diseases of the neuromuscular junction

Current Opinion in Pharmacology, 2002
The neuromuscular junction is a prototype synapse and it is also the site of well-characterised autoimmune and hereditary disorders. In the presynaptic terminal, voltage-gated potassium channels and voltage-gated calcium channels are subtly altered in genetic disorders and mutations in the enzyme that synthesises acetylcholine have been demonstrated in
McConville, J, Vincent, A
openaire   +3 more sources

DIAGNOSIS IN NEUROMUSCULAR DISEASES

Neurologic Clinics, 1996
The diagnosis of neuromuscular diseases can be challenging and successful in the majority of patients, due to advancements in electrophysiology, muscle and nerve biopsy immunohistochemistry, and cytogenetics. This article reviews diverse topics, highlighting these recent achievements, with an emphasis on how they affect the clinical and laboratory ...
D S, Younger, P H, Gordon
openaire   +2 more sources