Results 271 to 280 of about 100,070 (325)

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Neuromuscular dysfunction in patient-derived FUS^R244RR-ALS iPSC model via axonal downregulation of neuromuscular junction proteins. [PDF]

NAR Mol Med
von Kügelgen N, Ludwik K, Mendonsa S, Römer C, Becher E, Breimann L, Strauch M, Mari T, Mongellaz S, Zuckerman B, Efendic F, Grexa N, Oliveras-Martinez A, Woehler A, Selbach M, La Bella V, Ulitsky I, Chekulaeva M.   +17 more
europepmc   +1 more source

Changes in brainstem habituation during onabotulinumtoxinA treatment in chronic migraine: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Chronic migraine is a debilitating neurological disorder characterized by central sensitization and impaired brainstem habituation. OnabotulinumtoxinA is an established prophylactic treatment for chronic migraine, yet its effects on central trigeminal sensory processing remain incompletely understood.
Gerlinde Freimark, Sebastian Strauss, Lucas H. Overeem, Mira P. Fitzek, Kristin S. Lange, Carolin L. Höhne, Uwe Reuter, Robert Fleischmann, Bianca Raffaelli   +8 more
wiley   +1 more source

Sensory modulation of neuropeptide signaling by CASY-1 gates cholinergic transmission at <i>Caenorhabditis elegans</i> neuromuscular junction. [PDF]

J Biosci
Shahi N, Thapliyal S, Babu K.
europepmc   +1 more source

Nurses' Role in Transitional Care During Intensive Care Unit Family Meetings for Patients With Prolonged Mechanical Ventilation

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To describe nurses' roles in transitional care planning during intensive care unit (ICU) family meetings for patients with prolonged mechanical ventilation (PMV). Design A qualitative descriptive study. Methods Using secondary data from a trial of a decision aid about PMV, transcripts from 19 unstructured ICU family meetings were ...
HyunBin You, Sharron L. Docherty, Deepshikha C. Ashana, Wei Pan, Christopher E. Cox, Tolu O. Oyesanya   +5 more
wiley   +1 more source

Motor unit adaptation to disuse: crossing the threshold from firing rate suppression to neuromuscular junction transmission. [PDF]

J Physiol
Piasecki M.
europepmc   +1 more source

Safe Mobility in Hospitalised Older Adults: A Concept Analysis

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To conduct a concept analysis of ‘safe mobility’, with specific application in hospitalised older adults, identifying its defining attributes, antecedents and consequences. Background The promotion of safe mobility is essential for maintaining the functionality of hospitalised older adults.
Esther Mourão Nicoli, Frances Valéria Costa e Silva, Rosane Barreto Cardoso, Tallita Mello Delphino, Luciana Guimarães Assad, Samara Gonçalves de Oliveira   +5 more
wiley   +1 more source

An α7 nicotinic and GABA_B receptor-mediated pathway controls acetylcholine release in the tripartite neuromuscular junction. [PDF]

J Physiol
Petrov K, Lenina O, Leroy J, Bernard V, Germain T, Truong C, Nurullin L, Sibgatullina G, Ohno K, Samigullin D, Krejci E.   +10 more
europepmc   +1 more source

Reviewer #3 (Public Review): Depletion of SMN protein in mesenchymal progenitors impairs the development of bone and neuromuscular junction in spinal muscular atrophy

openalex   +1 more source

Crosstalk among canonical Wnt and Hippo pathway members in skeletal muscle and at the neuromuscular junction. [PDF]

Neural Regen Res
Hashemolhosseini S, Gessler L.
europepmc   +1 more source