Results 291 to 300 of about 98,850 (323)
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Cholinesterases of neuromuscular junction
Neurochemistry International, 1980The ultrastructural localization of AChE and BuChE was studied in motor endplates of the rat and mouse diaphragms, using the CNS(?) modification of the one-step Cu-thiocholine procedure. AChE activity was observed on pre- and postsynaptic membranes, in the basal lamina and in the Schwann cell-nerve terminal interspace.
M, Brzin +3 more
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Development of the neuromuscular junction
Cell and Tissue Research, 2006The differentiation of the neuromuscular junction is a multistep process requiring coordinated interactions between nerve terminals and muscle. Although innervation is not needed for muscle production, the formation of nerve-muscle contacts, intramuscular nerve branching, and neuronal survival require reciprocal signals from nerve and muscle to ...
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Neuromuscular Junction Disorders
PM&R, 2013AbstractDisorders of the neuromuscular junction, such as myasthenia gravis and Lambert‐Eaton myasthenic syndrome, constitute an important and treatable class of diseases. Both disorders are typically caused by an immunologically mediated attack on discrete components of the neuromuscular junction, compromise the efficacy of neurotransmitter ...
Chiawen Lucy, Liang, Steve, Han
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Neuromuscular junction disorders
2016Diseases of the neuromuscular junction comprise a wide range of disorders. Antibodies, genetic mutations, specific drugs or toxins interfere with the number or function of one of the essential proteins that control signaling between the presynaptic nerve ending and the postsynaptic muscle membrane.
Jan, Verschuuren +2 more
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Watching the neuromuscular junction
Journal of Neurocytology, 2003To understand how synapses form, it is important to be able to watch them as they form. Transgenic mice in which motor axons are indelibly labeled with the Green Fluorescent Protein (GFP) or one of its spectral variants (XFPs) provide a new way to image motor nerve terminals; when combined with contrasting stains for the postsynaptic membrane, both pre-
Jeff W, Lichtman, Joshua R, Sanes
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Acetylcholinesterase in the neuromuscular junction
Chemico-Biological Interactions, 1999New findings regarding acetylcholinesterase (AChE) in the neuromuscular junction (NMJ), obtained in the last decade, are briefly reviewed. AChE is highly concentrated in the NMJs of vertebrates. Its location remains stable after denervation in mature rat muscles but not in early postnatal muscles.
R, Gaspersic +3 more
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Neuromuscular junctions in the leech
Journal of Comparative Neurology, 1973AbstractNeuromuscular junctions on leech body wall muscle have been described. Based on vesicle morphology, there are two types of junctions, (I) clear vesicle terminals, and (II) dense core vesicle terminals. Further, the dense core terminals are‐of two types, (1) small terminals which appear to directly innervate body wall muscle cells, and (2) large
B A, Yaksta-Sauerland, R E, Coggeshall
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Neuromuscular junctional disorders
The Indian Journal of Pediatrics, 2008Neuromuscular junctional disorders (NMJ) in children are distinct entity. They may be acquired or hereditary. They pose problem in diagnosis because of the higher occurrence of sero negative Myasthenia Gravis (MG) cases in children. The identity of MusK antibody positivity in a good percentage of sero negative cases further adds to problems in ...
A S, Girija, V V, Ashraf
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Glycobiology of the neuromuscular junction
Journal of Neurocytology, 2003Most molecules that are present at synapses are glycosylated with carbohydrates, and some carbohydrate structures are themselves uniquely synaptic in their localization. Thus, proteins or lipids at the synapse may bear distinct carbohydrates that alter their localization or function.
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Neuromuscular Junction Disordersa
2015Abstract The neuromuscular junction (NMJ) is a critical component of the motor unit that is made up of the distal, unmyelinated nerve terminal, synaptic space, and end-plate region of the muscle fiber. Contraction of muscle fiber involves a coordinated series of steps that ultimately generates an action potential at the muscle end plate (
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