Results 111 to 120 of about 1,162 (153)

Prolonged paralysis due to nondepolarizing neuromuscular blocking agents and corticosteroids

open access: closedMuscle & Nerve, 1994
AbstractThe long‐term use of nondepolarizing neuromuscular blocking agents (ND‐NMBA) has recently been implicated as a cause of prolonged muscle weakness, although the site of the lesion and the predisposing factors have been unclear. We report 3 patients (age 37–52 years) with acute respiratory insufficiency who developed prolonged weakness following ...
Richard J. Barohn   +4 more
openalex   +4 more sources

Fumarates: Unique nondepolarizing neuromuscular blocking agents that are antagonized by cysteine

open access: closedJournal of Critical Care, 2009
It has been almost 20 years since the introduction of the last new nondepolarizing neuromuscular blocking agent into clinical practice, and research is ongoing to fill a clinical need for a nondepolarizing agent with a fast onset of effect and a short duration of action, as described by Savarese and Kitz [1] in 1975.
Cynthia A. Lien   +4 more
openalex   +4 more sources

Resistance to Nondepolarizing Neuromuscular Blocking Agents

open access: closedPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1996
Several case reports of resistance to short‐term administration of nondepolarizing neuromuscular blocking agents (NNMBAs) have been reported in research and surgical settings. Recently, several reports documented resistance to NNMBAs during therapy for prolonged paralysis in critically ill patients. Adverse outcomes associated with NNMBA resistance may
Suzanne J. Tschida   +3 more
openalex   +3 more sources

Nondepolarizing Neuromuscular Blocking Agents, Reversal, and Risk of Postoperative Pneumonia

open access: closedSurvey of Anesthesiology, 2017
AbstractBackgroundResidual postoperative paralysis from nondepolarizing neuromuscular blocking agents (NMBAs) is a known problem. This paralysis has been associated with impaired respiratory function, but the clinical significance remains unclear. The aims of this analysis were two-fold: (1) to investigate if intermediate-acting NMBA use during surgery
Catherine M. Bulka   +5 more
openalex   +4 more sources

Inhibition of human plasma cholinesterase and erythrocyte acetylcholinesterase by nondepolarizing neuromuscular blocking agents

open access: closedJournal of Anesthesia, 2000
The kinetics of the inhibition of human plasma cholinesterase (ChE) and erythrocyte acetylcholinesterase (AChE) by alcuronium, atracurium, d-tubocurarine, pancuronium, pipecuronium, and vecuronium were studied in blood drawn from 35 surgical patients.The activities of plasma ChE and erythrocyte AChE were determined by the calorimetric method of Ellman ...
Masato Kato   +5 more
openalex   +4 more sources

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